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循证医学更新:切开复位与闭合复位

Evidence based update: open versus closed reduction.

作者信息

Ghayoumi Pouriya, Kandemir Utku, Morshed Saam

机构信息

University of California, San Francisco School of Medicine, United States.

University of California, San Francisco, Orthopaedic Trauma Institute at San Francisco General Hospital, United States.

出版信息

Injury. 2015 Mar;46(3):467-73. doi: 10.1016/j.injury.2014.10.011. Epub 2014 Oct 14.

Abstract

Outcomes after operative treatment of displaced femoral neck fractures in young adults are fraught with high complications rates including non-union and avascular necrosis. Among the therapeutic controversies that persist is the role of open reduction, which would allow surgeons a direct means to improve the quality of reduction, a predictor of successful treatment. We performed a systematic review of the literature to compare the outcomes (nonunion, avascular necrosis, and deep infection) after open reduction with internal fixation (ORIF) to closed reduction with internal fixation (CRIF) of acute (surgery performed less than 6 weeks from injury) femoral neck fractures in young adults (average age of 50 or younger) followed for at least one year. Despite the large literature investigating outcomes after operative treatment of femoral neck fracture, relatively few studies aimed to determine the relative risk of complications associated with method of reduction. Therefore, both observational and randomised studies as well as case series with clear descriptions of surgical approach and outcomes were included. We identified 21 studies that matched our inclusion criteria. The incidence of nonunion was 11.6% in closed reduction and 14.9% in the open reduction group (P=0.25). The incidence of avascular necrosis for CRIF and ORIF were 17.2% and 17.7% respectively (P=0.91). The incidence of deep wound infection was 0.49% in the closed reduction group and 3.9% in the open reduction group (P=0.0019). Meta-analysis of risk ratios estimated from six of the studies with comparative data revealed no significant difference in the incidence of nonunion, avascular necrosis or total complications between the two reduction techniques. In summary, systematic review of the literature reveals a lack of evidence in support of ORIF versus CRIF as a means of treating displaced femoral neck fractures in young patients with respect to union and avascular necrosis; however, the incidence of surgical site infections may be lower with CRIF. Firm conclusions cannot be drawn given the lack of high quality prospective studies and patient reported outcomes. In the future, randomised controlled trials will be required to test the effect of reduction method.

摘要

年轻成人移位型股骨颈骨折手术治疗后的结果充满了高并发症发生率,包括骨不连和缺血性坏死。持续存在的治疗争议之一是切开复位的作用,切开复位能让外科医生有直接手段提高复位质量,而复位质量是治疗成功的一个预测因素。我们对文献进行了系统回顾,以比较切开复位内固定(ORIF)与闭合复位内固定(CRIF)治疗年轻成人(平均年龄50岁及以下)急性(受伤后6周内手术)股骨颈骨折且随访至少一年后的结果(骨不连、缺血性坏死和深部感染)。尽管有大量文献研究股骨颈骨折手术治疗后的结果,但相对较少的研究旨在确定与复位方法相关的并发症相对风险。因此,纳入了观察性和随机研究以及对手术方法和结果有清晰描述的病例系列。我们确定了21项符合我们纳入标准的研究。闭合复位组骨不连发生率为11.6%,切开复位组为14.9%(P = 0.25)。CRIF和ORIF的缺血性坏死发生率分别为17.2%和17.7%(P = 0.91)。闭合复位组深部伤口感染发生率为0.49%,切开复位组为3.9%(P = 0.0019)。对六项有比较数据的研究估计的风险比进行荟萃分析显示,两种复位技术在骨不连、缺血性坏死或总并发症发生率上无显著差异。总之,文献系统回顾显示,在年轻患者中,就骨愈合和缺血性坏死而言,缺乏证据支持ORIF优于CRIF作为治疗移位型股骨颈骨折的方法;然而,CRIF的手术部位感染发生率可能较低。鉴于缺乏高质量的前瞻性研究和患者报告的结果,无法得出确凿结论。未来,将需要随机对照试验来测试复位方法的效果。

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