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马的指深屈肌腱内低场磁共振成像异常与大体及组织学变化相关吗?

Do low field magnetic resonance imaging abnormalities correlate with macroscopical and histological changes within the equine deep digital flexor tendon?

作者信息

Sherlock C E, Mair T S, Ireland J, Blunden T

机构信息

Bell Equine Veterinary Clinic, Mereworth, Kent ME18 5GS, UK.

Bell Equine Veterinary Clinic, Mereworth, Kent ME18 5GS, UK.

出版信息

Res Vet Sci. 2015 Feb;98:92-7. doi: 10.1016/j.rvsc.2014.12.008. Epub 2014 Dec 16.

DOI:10.1016/j.rvsc.2014.12.008
PMID:25555604
Abstract

Correlating magnetic resonance (MR) imaging and histopathological findings is essential to validate low field MR imaging in lame horses. This study aimed to compare signal changes in the deep digital flexor tendon (DDFT) of the distal limb on low field MR imaging with macroscopical and histological findings. Cadaver limbs from lame horses with DDFT lesions were selected. The DDFT MR imaging findings and histopathological results were graded, and macroscopical abnormalities were recorded. There was a strong correlation between MR imaging and histopathology grades (rs = 0.76, p < 0.001) in the foot. There was moderate agreement (Kappa statistic 0.52) between the MR and histopathology grades; agreement was superior further proximal in the foot. The presence and severity of pathology in the DDFT are well represented by the presence and severity of MR imaging signal changes. The study supports the use of low field MR imaging for diagnosis of equine distal limb DDFT lesions.

摘要

将磁共振(MR)成像与组织病理学结果相关联对于验证低场MR成像在跛马中的应用至关重要。本研究旨在比较低场MR成像时远端肢体的指深屈肌腱(DDFT)信号变化与大体及组织学结果。选取患有DDFT病变的跛马尸体肢体。对DDFT的MR成像结果和组织病理学结果进行分级,并记录大体异常情况。足部的MR成像与组织病理学分级之间存在强相关性(rs = 0.76,p < 0.001)。MR和组织病理学分级之间存在中度一致性(Kappa统计量为0.52);在足部更近端处一致性更好。DDFT中病变的存在及严重程度可通过MR成像信号变化的存在及严重程度得到很好的体现。本研究支持使用低场MR成像诊断马远端肢体DDFT病变。

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