一项基于人群的印度泰米尔纳德邦三个地区人乳头瘤病毒（HPV）患病率研究。
A population-based study of the prevalence of HPV in three districts of Tamil Nadu, India.
作者信息
Sureshkumar Belli T, Shanmughapriya Santhanam, Das Bhudev C, Natarajaseenivasan Kalimuthusamy
机构信息
Medical Microbiology Laboratory, Department of Microbiology, School of Life Sciences, Bharathidasan University, Tiruchirappalli, India; Department of Microbiology, Vivekananda College of Arts and Science, Tiruchengode, India.
Medical Microbiology Laboratory, Department of Microbiology, School of Life Sciences, Bharathidasan University, Tiruchirappalli, India.
出版信息
Int J Gynaecol Obstet. 2015 Apr;129(1):58-61. doi: 10.1016/j.ijgo.2014.10.025. Epub 2014 Dec 22.
OBJECTIVE
To evaluate the prevalence of HPV infection among women from three districts of Tamil Nadu (Erode, Salem, and Namakkal).
METHODS
Between January 27, 2007, and December 15, 2009, 1800 women aged 20-70years who had normal cervical cytology were enrolled into a cross-sectional study. Participants completed interviews and provided first void urine samples for assessment of HPV infection.
RESULTS
Among 1699 eligible samples, 179 (10.5%) were HPV positive. HPV16 was the most common type (affecting 68 [4.0%] women), followed by HPV6 (58 [3.4%]). Among the 179 HPV-positive women, 71 (39.7%) were aged 36-45years. An annual income of less than 25 000 INR was significantly associated with HPV infection in all three districts (P<0.05). Regular intercourse was also associated with HPV in Erode and Salem (P<0.05).
CONCLUSION
Screening and prophylactic vaccines containing HPV16 and HPV6 should be promoted in western Tamil Nadu.
目的
评估泰米尔纳德邦三个地区（埃罗德、塞勒姆和纳马卡尔）女性人乳头瘤病毒（HPV）感染的流行情况。
方法
在2007年1月27日至2009年12月15日期间，1800名年龄在20至70岁之间、宫颈细胞学检查正常的女性被纳入一项横断面研究。参与者完成访谈并提供首次晨尿样本以评估HPV感染情况。
结果
在1699份合格样本中，179份（10.5%）HPV呈阳性。HPV16是最常见的类型（感染68名[4.0%]女性），其次是HPV6（58名[3.4%]）。在179名HPV阳性女性中，71名（39.7%）年龄在36至45岁之间。在所有三个地区，年收入低于25000印度卢比与HPV感染显著相关（P<0.05）。在埃罗德和塞勒姆，规律性交也与HPV感染相关（P<0.05）。
结论
应在泰米尔纳德邦西部推广包含HPV16和HPV6的筛查及预防性疫苗。
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