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印度大学生对人乳头瘤病毒、人乳头瘤病毒疫苗和宫颈癌的知识、认知及态度

Knowledge, Awareness and Attitude on HPV, HPV Vaccine and Cervical Cancer among the College Students in India.

作者信息

Rashid Shazia, Labani Satyanarayana, Das Bhudev C

机构信息

Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida, India.

Department of Epidemiology and Biostatistics, Institute of Cytology and Preventive Oncology (ICPO), Uttar Pradesh, Noida, India.

出版信息

PLoS One. 2016 Nov 18;11(11):e0166713. doi: 10.1371/journal.pone.0166713. eCollection 2016.

Abstract

BACKGROUND

Infection of specific high risk Human papillomaviruses (HPVs) is known to cause cervical cancer and two prophylactic vaccines have been developed against two major high risk HPV types 16 and 18 for prevention of cervical cancer. Because of societal, religious and ethical issues associated with the vaccination of adolescent girls in India together with lack of awareness about HPV and HPV vaccines, no successful HPV immunization program has been employed in India.

OBJECTIVE

To determine knowledge, awareness and attitude of college students on HPV, HPV vaccine and cervical cancer.

METHOD

A questionnaire-based survey was conducted in a total of 1580 undergraduate students between the age group 16-26 years comprising 684 girls and 876 boys.

RESULTS

Out of a total of 1580 students, girls had more knowledge about cervical cancer (82.45%, p<0.001), HPV (45.61%, p<0.001) and HPV vaccines (44%, p<0.001) when compared to those in boys. However, knowledge about the types of HPV and vaccines was poor. Interestingly, students from biology-major had more knowledge and awareness about cervical cancer (81.89%, p<0.001) and HPV (46.58%, <0.001) when compared to non-biology students. Girls from both biology and non-biology group had higher awareness compared to boys. Analysis of odds ratio (ORs) along with 95% CI showed older girls with 1.2 to 3 fold (p<0.05) higher knowledge than boys. All students agreed that girls should get vaccinated against HPV (p<0.001).

CONCLUSION

It is suggested that there is a need for educational intervention and awareness campaigns to augment HPV immunization program for control of cervical cancer in India.

摘要

背景

已知特定高危型人乳头瘤病毒(HPV)感染会引发宫颈癌,并且已经研发出两种预防性疫苗,用于预防由两种主要高危HPV类型16型和18型引起的宫颈癌。由于印度在少女疫苗接种方面存在社会、宗教和伦理问题,同时人们对HPV及HPV疫苗缺乏认识,因此印度尚未实施成功的HPV免疫接种计划。

目的

确定大学生对HPV、HPV疫苗和宫颈癌的知识、认识及态度。

方法

对1580名年龄在16 - 26岁之间的本科生进行了问卷调查,其中包括684名女生和876名男生。

结果

在总共1580名学生中,与男生相比,女生对宫颈癌(82.45%,p<0.001)、HPV(45.61%,p<0.001)和HPV疫苗(44%,p<0.001)的了解更多。然而,对HPV类型和疫苗的了解程度较低。有趣的是,与非生物专业学生相比,生物专业的学生对宫颈癌(81.89%,p<0.001)和HPV(46.58%,<0.001)的知识和认识更多。生物专业和非生物专业的女生的认识都高于男生。优势比(ORs)连同95%置信区间的分析显示,年龄较大的女生的知识水平比男生高1.2至3倍(p<0.05)。所有学生都认为女孩应该接种HPV疫苗(p<0.001)。

结论

建议在印度开展教育干预和宣传活动,以加强HPV免疫接种计划,从而控制宫颈癌。

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