Giménez-Manzorro Álvaro, Romero-Jiménez Rosa María, Calleja-Hernández Miguel Ángel, Pla-Mestre Rosa, Muñoz-Calero Alberto, Sanjurjo-Sáez María
Pharmacy Department, Hospital General Universitario Gregorio Marañón, C/Dr. Esquerdo 46, 28007, Madrid, Spain,
Int J Clin Pharm. 2015 Feb;37(1):159-67. doi: 10.1007/s11096-014-0057-0. Epub 2015 Jan 4.
Medication reconciliation is a key tool in the prevention of adverse drug events.
To assess the impact of an electronic reconciliation tool in decreasing unintended discrepancies between medications prescribed after surgery and the patient's usual treatment.
General Surgery Department of Gregorio Marañón's University General Hospital, Madrid.
A pre-post intervention study with no equivalent control group was carried out between June 2009 and December 2010. Patients hospitalized in the General Surgery Department for 24 h or more, and whose prescriptions prior to admission included three or more drugs were included in the study. Patients were interviewed to gather information about their usual treatment drugs. Discrepancies between the latter and the drugs prescribed after surgery were assessed before and after the medication reconciliation electronic tool was implemented.
Proportion of patients with at least one unintended discrepancy.
A total of 107 patients in the pre-intervention phase and 84 patients in the post-intervention phase were included. We detected 1,678 discrepancies, 167 were found to be unintended. The number of patients with at least one unintended discrepancy was 43 (40.2 %) in the pre-intervention phase, and 38 (38.1 %) in the post-intervention phase, p = 0.885. The percentage of unintended discrepancies over the total amount of drugs reconciled was lower in the post-intervention phase than in the pre-intervention phase (6.6 vs. 10.6 %), p = 0.002. Regarding unintended discrepancies 79.2 % were grade C severity (the error reached the patient but caused no harm), 13.6 % grade D (the error reached the patient and required monitoring or intervention to preclude harm) and 7.1 % grade E (the error may have contributed to or resulted in temporary harm to the patient and required intervention).
Implementation of an electronic tool facilitated the process of medication reconciliation in a general surgery unit. The proportion of unintended discrepancies over the total amount of drugs reconciled was reduced after the implementation of the reconciliation programme. However, we could not demonstrate a more significant impact due to some methodological limitations.
用药核对是预防药物不良事件的关键工具。
评估电子核对工具对减少术后处方药物与患者常规治疗之间意外差异的影响。
马德里格雷戈里奥·马拉尼翁大学综合医院普通外科。
2009年6月至2010年12月期间进行了一项无前瞻性对照的干预前后研究。纳入在普通外科住院24小时或更长时间且入院前处方包含三种或更多药物的患者。对患者进行访谈以收集其常规治疗药物的信息。在实施用药核对电子工具前后评估后者与术后处方药物之间的差异。
至少有一项意外差异的患者比例。
干预前阶段共纳入107例患者,干预后阶段纳入84例患者。我们检测到1678处差异,其中167处被发现是意外的。干预前阶段至少有一项意外差异的患者数量为43例(40.2%),干预后阶段为38例(38.1%),p = 0.885。干预后阶段意外差异在核对的药物总量中所占百分比低于干预前阶段(6.6%对10.6%),p = 0.002。关于意外差异,79.2%为C级严重程度(错误到达患者但未造成伤害),13.6%为D级(错误到达患者且需要监测或干预以避免伤害),7.1%为E级(错误可能导致或已导致患者暂时伤害且需要干预)。
电子工具的实施促进了普通外科病房的用药核对过程。核对方案实施后,意外差异在核对的药物总量中所占比例有所降低。然而,由于一些方法学上的局限性,我们未能证明有更显著的影响。