Mabuchi N, Hamada T, Yoshioka H
Nihon Igaku Hoshasen Gakkai Zasshi. 1989 Sep 25;49(9):1122-40.
The purpose of this study is to evaluate the possibility of qualitative diagnosis in hepatic tumors by fast magnetic resonance (MR) imaging with suspended respiration using partial flip angle and gradient echo technique at 0.5 T. Fast MR imaging does not replace conventional spin-echo procedures, but is complementary to it. For the analysis of contrast as a function of flip angle, 32 hepatocellular carcinomas (HCCs) of nodular type and 11 hemangiomas were examined with flip angles of 20, 40 and 60 degrees on sagittal images. In general, the lesions showed relatively high and low intensities on the images with flip angles of 20 and 60 degrees, respectively. On the images with flip angle of 40 degrees, signal-to-noise (S/N) ratio was higher, but contrast between tumor and liver was lesser than with that of other angles. The change of contrast-to-noise (C/N) ratio between the flip angles of 20 and 60 degrees in hemangiomas was larger than that in HCCs, significantly. It was useful for evaluation of lesions to observe the change of C/N ratio, and it was necessary for detection of lesions to obtain the images with at least three flip angles. For dynamic MR imaging, 18 HCCs including 5 cases after transcatheter chemoembolization (TCE) and 5 hemangiomas were examined with flip angle of 40 degrees. With employment of Gd-DTPA, S/N ratio and contrast were improved in many cases, and hemodynamics of tumors was able to be observed. It was suggested that dynamic MR imaging was useful especially in evaluation of efficacy of TCE using lipiodol.
本研究的目的是评估在0.5T场强下使用部分翻转角和梯度回波技术进行屏气快速磁共振(MR)成像对肝脏肿瘤进行定性诊断的可能性。快速MR成像并不能替代传统的自旋回波检查,而是与之互补。为了分析作为翻转角函数的对比情况,在矢状位图像上对32个结节型肝细胞癌(HCC)和11个血管瘤分别采用20°、40°和60°的翻转角进行检查。一般来说,在翻转角为20°和60°的图像上,病变分别表现为相对高信号和低信号。在翻转角为40°的图像上,信噪比(S/N)较高,但肿瘤与肝脏之间的对比低于其他角度。血管瘤在20°和60°翻转角之间的对比噪声(C/N)比变化明显大于HCC。观察C/N比的变化对病变评估有用,且为检测病变至少获取三个翻转角的图像是必要的。对于动态MR成像,对18个HCC(包括5例经动脉化疗栓塞术(TCE)后病例)和5个血管瘤采用40°翻转角进行检查。使用钆喷酸葡胺(Gd-DTPA)后,许多病例的S/N比和对比得到改善,并且能够观察到肿瘤的血流动力学。提示动态MR成像尤其在评估使用碘油的TCE疗效方面有用。