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澳大利亚水氟化作用有效性的当代多层次分析。

Contemporary multilevel analysis of the effectiveness of water fluoridation in Australia.

作者信息

Do Loc, Spencer A John

机构信息

Australian Research Centre for Population Oral Health, The University of Adelaide, South Australia.

出版信息

Aust N Z J Public Health. 2015 Feb;39(1):44-50. doi: 10.1111/1753-6405.12299. Epub 2015 Jan 5.

Abstract

AIMS

Water fluoridation was extended in Queensland, Australia, across 2009-2011. A research program was commenced to inform the rationale for and the outcome of this program, to estimate the effectiveness of water fluoridation in preventing caries and to predict changes in caries experience as a result of the extension of fluoridation.

METHODS

Queensland children were selected through a stratified random sample selection in 2010-2012. Oral epidemiological examinations provided individual-level outcomes for decayed, missing or filled primary or permanent tooth surfaces: dmfs (among 5-8-year-olds) and DMFS (9-14-year-olds). Explanatory factors at the individual-level, school-level and area-level fluoridation status were derived. Data were weighted to represent the population. Three-level multilevel multivariable models were sequentially specified for negative binomial distribution of dmfs/DMFS to estimate rate ratios (RR). The effectiveness of area-level water fluoridation was evaluated in the full models controlling for other factors.

RESULTS

Data from 2,214 5-8 year-olds and 3,186 9-14 year-olds from 207 schools in 16 areas were analysed. Queensland's average dmfs was 4.23 and DMFS 1.47. The lowest levels of dental caries were observed in long-term fluoridated Townsville. In the full models, Townsville children had significantly lower caries experience (RR for dmfs: 0.61 (95%CI: 0.44-0.82); RR for DMFS 0.60 (95%CI: 0.42-0.88)) compared with children in non-fluoridated areas.

CONCLUSION

Comparison of caries experience of children at the time of the extension of water fluoridation supported the rationale for this population health measure.

摘要

目的

2009 - 2011年期间,澳大利亚昆士兰州扩大了水氟化项目。启动了一项研究计划,以阐明该项目的基本原理和结果,评估水氟化在预防龋齿方面的有效性,并预测由于氟化范围扩大导致的龋齿患病情况变化。

方法

2010 - 2012年通过分层随机抽样选取昆士兰州儿童。口腔流行病学检查提供了个体层面龋齿、缺失或填充的乳牙或恒牙牙面的结果:dmfs(5 - 8岁儿童)和DMFS(9 - 14岁儿童)。得出个体层面、学校层面和地区层面的氟化状况等解释因素。数据进行加权以代表总体人群。针对dmfs/DMFS的负二项分布依次指定三级多水平多变量模型来估计率比(RR)。在控制其他因素的完整模型中评估地区层面水氟化的有效性。

结果

分析了来自16个地区207所学校的2214名5 - 8岁儿童和3186名9 - 14岁儿童的数据。昆士兰州的平均dmfs为4.23,DMFS为1.47。在长期进行水氟化的汤斯维尔观察到龋齿水平最低。在完整模型中,与未氟化地区的儿童相比,汤斯维尔儿童的龋齿患病情况显著更低(dmfs的RR:0.61(95%CI:0.44 - 0.82);DMFS的RR:0.60(95%CI:0.42 - 0.88))。

结论

水氟化扩展时儿童龋齿患病情况的比较支持了这项人群健康措施的基本原理。

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