Zhou Zhi-Hong, Liu Min-Zhuo, Wang Meng-Hua, Qu Wei, Sun Jian-Bo, Liang Jing-Yu, Wu Fei-Hua
a Department of Natural Medicinal Chemistry , China Pharmaceutical University , #24 Tongjiaxiang, Nanjing 210009 P.R. China.
Nat Prod Res. 2015;29(9):795-9. doi: 10.1080/14786419.2014.986727. Epub 2015 Jan 6.
A new ellagic acid derivative, 3,3'-dimethylellagic acid-4'-O-(6″-galloyl)-β-D-glucoside, named runcinatside (5), together with four known compounds 3,3'-dimethylellagic acid (1), 3,3',4'-trimethylellagic acid (2), 3,3'-dimethylellagic acid-4'-O-β-D-glucoside (3) and 3-methylellagic acid-4'-O-α-L-rhamno-pyranoside (4), was isolated from the roots of Polygonum runcinatum Buch.-Ham. ex D.Don Var. sinense Hemsl and the structures of these compounds were established by spectroscopic methods and comparison with previously reported data. All compounds showed antioxidant activities in vitro and compound 5 possessed the highest activity.
从中华抱茎蓼（Polygonum runcinatum Buch.-Ham. ex D.Don Var. sinense Hemsl）的根中分离出一种新的鞣花酸衍生物3,3'-二甲基鞣花酸-4'-O-(6″-没食子酰基)-β-D-葡萄糖苷，命名为抱茎蓼苷（5），以及四种已知化合物3,3'-二甲基鞣花酸（1）、3,3',4'-三甲基鞣花酸（2）、3,3'-二甲基鞣花酸-4'-O-β-D-葡萄糖苷（3）和3-甲基鞣花酸-4'-O-α-L-鼠李糖苷（4），并通过光谱方法和与先前报道的数据比较确定了这些化合物的结构。所有化合物在体外均表现出抗氧化活性，化合物5具有最高活性。
