Saha Nemai, Chatterjee Bhaskar, Chattopadhyay Shital K
Department of Chemistry, University of Kalyani , Kalyani-741235, West Bengal, India.
J Org Chem. 2015 Feb 6;80(3):1896-904. doi: 10.1021/jo5022162. Epub 2015 Jan 15.
A building block approach for the synthesis of α,β-diamino acids is described, which involves the diastereodivergent preparation of two sets of orthogonally protected δ,ε-unsaturated α,β-diamino acids as templates for the preparation of 12 new α,β-diamino acids of biological relevance using simple techniques.
本文描述了一种用于合成α,β-二氨基酸的模块构建方法,该方法涉及非对映发散地制备两组正交保护的δ,ε-不饱和α,β-二氨基酸,作为使用简单技术制备12种具有生物学相关性的新型α,β-二氨基酸的模板。