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减少乳腺癌相关淋巴水肿风险和优化管理的监测建议。

Surveillance recommendations in reducing risk of and optimally managing breast cancer-related lymphedema.

机构信息

Sinclair School of Nursing, University of Missouri-Columbia, S235 School of Nursing Building, Columbia, MO 65211, USA.

Ellis Fischel Cancer Center, One Hospital Drive, Columbia, MO 65212, USA.

出版信息

J Pers Med. 2014 Aug 18;4(3):424-47. doi: 10.3390/jpm4030424.

Abstract

Breast cancer survivors are at increased risk for the development of breast cancer-related lymphedema (BCRL), a chronic, debilitating, and disfiguring condition that is progressive and requires lifelong self-management of symptoms. It has been reported that over 40% of the 2.5 million breast cancer survivors in the United States may meet the criteria for BCRL during their lifetimes. Ongoing surveillance, beginning with pre-operative assessment, has been effective in identifying subclinical lymphedema (LE). A prospective model for surveillance is necessary in order to detect BCRL at an early stage when there is the best chance to reduce risk or slow progression. Physical methods for monitoring and assessment, such as circumferential arm measures, perometry, bioimpedance; exercise programs; prophylactic and early-intervention compression garments; and referral for complete decongestive therapy are all interventions to consider in the development of a BCRL surveillance program. In addition, supportive-educative programs and interactive engagement for symptom self-management should also be implemented. The importance of interdisciplinary collaboration is integral to the success of an effective personalized medicine program in breast cancer-related lymphedema surveillance.

摘要

乳腺癌幸存者发生乳腺癌相关淋巴水肿(BCRL)的风险增加,BCRL 是一种慢性、使人虚弱和致残的疾病,呈进行性发展,需要终身自我管理症状。据报道,在美国 250 万乳腺癌幸存者中,超过 40%的人在其一生中可能符合 BCRL 的标准。从术前评估开始的持续监测已被证明能有效识别亚临床淋巴水肿(LE)。为了在早期发现 BCRL,此时有最好的机会降低风险或减缓进展,有必要建立一个前瞻性监测模型。监测和评估的物理方法,如周径臂测量、容积描记法、生物阻抗法;运动方案;预防性和早期干预性压缩衣;以及完全消肿治疗的转介,都是在制定 BCRL 监测计划时需要考虑的干预措施。此外,还应实施支持性教育计划和症状自我管理的互动参与。多学科合作对于乳腺癌相关淋巴水肿监测中有效实施个性化医学计划的成功至关重要。

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