Shah Chirag, Asha Wafa, Vicini Frank
Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, 10201 Carnegie Avenue, Cleveland, OH, 44106, USA.
Department of Radiation Oncology, King Hussein Cancer Center, Amman, Jordan.
Curr Oncol Rep. 2023 Mar;25(3):151-154. doi: 10.1007/s11912-023-01357-w. Epub 2023 Jan 25.
Breast cancer-related lymphedema (BCRL) can have a significant impact on breast cancer survivors quality of life. The purpose of this review is to evaluate diagnostic tools for the assessment of BCRL.
Multiple BCRL diagnostic tools are available, though older diagnostic tools have low sensitivity, limiting the ability for sub-clinical BCRL diagnosis while BIS and perometry have increased sensitivity and the ability to diagnose BCRL sub-clinically. Prospective studies have demonstrated such an approach coupled to early intervention is associated with low rates of chronic BCRL while a recently published randomized trial demonstrated that prospective surveillance with BIS coupled with early intervention reduced rates of chronic BCRL as compared to circumference measurements with compression garments. Prospective and randomized data support the use of prospective surveillance for BCRL. The strongest data available comes from the PREVENT trial and supports prospective BCRL surveillance with bioimpedance spectroscopy coupled to early intervention with a compression sleeve.
乳腺癌相关淋巴水肿（BCRL）会对乳腺癌幸存者的生活质量产生重大影响。本综述旨在评估用于BCRL评估的诊断工具。
有多种BCRL诊断工具，然而较旧的诊断工具敏感性较低，限制了亚临床BCRL的诊断能力，而生物电阻抗光谱分析（BIS）和周径测量法具有更高的敏感性以及亚临床诊断BCRL的能力。前瞻性研究表明，这种方法与早期干预相结合可降低慢性BCRL的发生率，而最近发表的一项随机试验表明，与使用压力衣进行周长测量相比，采用BIS进行前瞻性监测并结合早期干预可降低慢性BCRL的发生率。前瞻性和随机数据支持对BCRL进行前瞻性监测。现有最有力的数据来自PREVENT试验，支持采用生物电阻抗光谱分析对BCRL进行前瞻性监测，并结合使用压力袖套进行早期干预。
