Arora B, Sharma K K, Yadav M S, Arora D R
Indian J Pathol Microbiol. 1989 Jan;32(1):40-5.
The incidence of sex chromatin in tumour cell nuclei was estimated in twenty five cases each of carcinoma and fibroadenoma breast using haematoxylin and eosin, thionine, aceto-orcein and Papanicolaou's stains on imprint-smears. The sex chromatin incidence in fibroadenoma was found similar to that of normal breast tissue but the incidence markedly decreased in carcinoma breast. Undifferentiated tumours with histologic grade III, nuclear grade I, no lymphocytic infiltrate and involvement of overlying skin, nipple and areola were more often associated with low sex chromatin incidence. No relationship was observed between sex chromatin incidence and tumour size or axillary lymph node metastasis.
利用苏木精和伊红、硫堇、醋酸地衣红和巴氏染色法对25例乳腺癌和25例乳腺纤维腺瘤的印片涂片进行染色，以估计肿瘤细胞核中性染色质的发生率。结果发现，乳腺纤维腺瘤中性染色质的发生率与正常乳腺组织相似，但乳腺癌中的发生率明显降低。组织学分级为III级、核分级为I级、无淋巴细胞浸润且累及覆盖皮肤、乳头和乳晕的未分化肿瘤，更常与低性染色质发生率相关。未观察到性染色质发生率与肿瘤大小或腋窝淋巴结转移之间的关系。
