Lee Manyong, Suh Mee Kyung, Lee Myung Hyun, Lee Jin Soo, Moon So Young
Department of Neurology, Ajou University, School of Medicine, San 5, Woncheon-dong, Yeongtong-gu, Suwon, Kyungki-do 443-721, Republic of Korea.
Department of Neurology, Samsung Medical Center, Seoul, Republic of Korea.
J Clin Neurosci. 2015 Apr;22(4):758-60. doi: 10.1016/j.jocn.2014.09.023. Epub 2015 Jan 3.
Injury in the dominant language hemisphere typically leads to agraphia, however we report a patient with agraphia after injury to the right angular gyrus. A 71-year-old Korean woman presented with the complaint of an inability to write for the last 7 days. The patient had been illiterate for most of her life, but had started learning to write Hangul, the Korean alphabet, at a welfare center 3 years ago. On language screening she was unable to write although she could read, and other language functions showed no abnormalities. Brain MRI showed acute infarction in the right angular gyrus. Her writing patterns displayed features of surface agraphia, indicative of phoneme-to-grapheme conversion with phonetic writing of targets. Additionally, she manifested visual errors. A functional MRI indicated that her left hemisphere was language dominant. This patient experienced agraphia resulting from pure impairment of visuo-constructive function after acute infarction in the right angular gyrus.
通常情况下，优势语言半球受损会导致失写症，然而我们报告了一例右侧角回损伤后出现失写症的患者。一名71岁的韩国女性主诉在过去7天里无法书写。该患者一生大部分时间都是文盲，但3年前开始在一家福利中心学习书写韩文（韩语字母）。在语言筛查中，她虽然能阅读但无法书写，其他语言功能未显示异常。脑部MRI显示右侧角回急性梗死。她的书写模式表现出表层失写症的特征，表明在对目标进行语音书写时存在音素到字素的转换。此外，她还表现出视觉错误。功能MRI显示她的左半球为语言优势半球。该患者在右侧角回急性梗死后因视觉构建功能的单纯受损而出现失写症。
