Moss Caroline E, Fernandez-Caballero Sandra, Walker David
Department of ICM/Anaesthetics, UCLH, London, UK.
Department of ICM, UCLH, London, UK.
BMJ Case Rep. 2015 Jan 5;2015:bcr2014204998. doi: 10.1136/bcr-2014-204998.
A 68-year-old woman presented 3 weeks following unsuccessful transcatheter radiofrequency ablation (TcRFA) for treatment of her chronic atrial fibrillation. Neurological signs manifested on day 2 of admission with generalised tonic-clonic seizures and reduced Glasgow Coma Score. She was treated for presumed central nervous system (CNS) infection, intubated and transferred to the intensive care unit. CT of the head showed bilateral oedema secondary to acute embolic stroke. Blood cultures grew Streptococcus viridans, and lumbar puncture findings were consistent with CNS infection. Echocardiography showed only a septostomy puncture from the atrial fibrillation ablation procedure. Thoracic CT demonstrated air in the left atrium, consistent with the diagnosis of atrio-oesophageal fistula, a rarely reported iatrogenic complication of TcRFA. MRI of the head showed significant neurological injury with innumerable embolic infarcts. After discussion with her family regarding the significant neurological insult, and with no signs of any clinical improvement, the patient died on day 8 of admission.
一名68岁女性在经导管射频消融术(TcRFA)治疗慢性房颤失败3周后就诊。入院第2天出现神经系统症状,表现为全身性强直阵挛发作,格拉斯哥昏迷评分降低。她接受了针对疑似中枢神经系统(CNS)感染的治疗,插管并转入重症监护病房。头部CT显示急性栓塞性中风继发双侧水肿。血培养出草绿色链球菌,腰椎穿刺结果与CNS感染相符。超声心动图仅显示房颤消融术中的房间隔穿刺。胸部CT显示左心房有气体,符合心房食管瘘的诊断,这是TcRFA一种罕见的医源性并发症。头部MRI显示有严重的神经损伤,有无数栓塞性梗死灶。在与患者家属讨论了严重的神经损伤情况且无任何临床改善迹象后,患者于入院第8天死亡。