贲门失弛缓症：一种不可被遗忘的食管鳞状细胞癌风险因素。
Achalasia: a risk factor that must not be forgotten for esophageal squamous cell carcinoma.
作者信息
Ríos-Galvez Shareni, Meixueiro-Daza Arturo, Remes-Troche Jose Maria
机构信息
Laboratorio de Motilidad y Fisiologia Digestiva, Instituto de Investigaciones Medico Biologicas, Boca del Rio, Veracruz, Mexico.
Labortorio de Fisiologia Digestiva y Motilidad, Instituto de Investigaciones Medico Biologicas, Veracruz, Veracruz, Mexico.
出版信息
BMJ Case Rep. 2015 Jan 6;2015:bcr2014204418. doi: 10.1136/bcr-2014-204418.
Abstract
Alcohol and tobacco abuse are the main risk factors for esophageal squamous cell carcinoma (ESCC), but other conditions that induce chronic irritation of the esophageal mucosa have also been attributed to it. For example, long-standing achalasia increases 16 times the risk of developing ESCC. We report the case of a patient with long-standing achalasia who developed ESCC. Although this complication is infrequent, it should be remembered by clinicians who treat patients with achalasia to detect early stages cancer.
摘要
酗酒和吸烟是食管鳞状细胞癌（ESCC）的主要危险因素，但其他导致食管黏膜慢性刺激的情况也被认为与该病有关。例如，长期贲门失弛缓症会使患食管鳞状细胞癌的风险增加16倍。我们报告了一例长期患有贲门失弛缓症并发展为食管鳞状细胞癌的患者。尽管这种并发症并不常见，但治疗贲门失弛缓症患者的临床医生应予以关注，以便早期发现癌症。
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