Corti R E, Monastra L, Fernández Marty P, Barco J C, Ferro F E, Galindo F, Musi A O, Kogan Z
Sección Esófago-Estómago, Hospital de Gastroenterología, Bonorino Udaondo, Capital Federal Argentina.
Acta Gastroenterol Latinoam. 1992;22(2):115-8.
During the period included between January 1970 and December 1990, we studied 242 patients with manometric and radiological diagnosis of esophageal achalasia. Eight of these patients (3.3%) developed during the evolution of their disease an esophageal carcinoma. Eight cases showed histologic type of epidermoid carcinoma: 3 differentiated, 3 semi-differentiated and 2 anaplastic. Therapy for achalasia was: one patient, Heller myotomy, 4 patients, dilatations with bougies in numerous opportunities, and the other two patients receive no treatment for achalasia. Two patients reported tracheobronchial fistulas as complication of carcinoma. Treatment received for carcinoma included: three patients, radiotherapy (4000 rads); one patient, chemotherapy; one patient, chemotherapy and radiotherapy, one resection surgery and two patients feeding gastrostomy. All of the eight patients died within the year of diagnosis of epidermoid carcinoma.
在1970年1月至1990年12月期间,我们研究了242例经测压和放射学诊断为贲门失弛缓症的患者。其中8例患者(3.3%)在疾病进展过程中发生了食管癌。8例显示为表皮样癌组织学类型:3例分化型,3例半分化型,2例未分化型。贲门失弛缓症的治疗方法为:1例患者行赫勒肌切开术,4例患者多次进行探条扩张,另外2例患者未接受贲门失弛缓症治疗。2例患者报告气管支气管瘘为癌症并发症。针对癌症的治疗包括:3例患者接受放射治疗(4000拉德);1例患者接受化疗;1例患者接受化疗和放疗,1例行切除手术,2例患者行胃造口喂养。所有8例患者均在表皮样癌诊断后的一年内死亡。