Structural Biology Brussels, Vrije Universiteit Brussel (VUB), 1050 Brussels, Belgium; Structural Biology Research Center, VIB, 1050 Brussels, Belgium.
Structure. 2015 Jan 6;23(1):7-9. doi: 10.1016/j.str.2014.12.007.
In this issue of Structure, Glatt and colleagues report the structure of the Kti11/Kti13 heterodimer. This study reveals how dimerization and Fe(2+) binding are required for modification of both tRNA and EF2, thus suggesting a mechanism for regulation of translation elongation via two different pathways.
本期《结构》杂志报道了 Kti11/Kti13 异二聚体的结构。该研究揭示了二聚化和 Fe(2+)结合如何修饰 tRNA 和 EF2，从而为通过两种不同途径调节翻译延伸提供了一种机制。
