Hsu Chi-Hsin, Chen Rebecca I, Lin Shan C
aDepartment of Ophthalmology, University of California, San Francisco, California, USA bDepartment of Ophthalmology, Taipei Medical University Shuang Ho Hospital, New Taipei City, Taiwan cCase Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Curr Opin Ophthalmol. 2015 Mar;26(2):90-5. doi: 10.1097/ICU.0000000000000124.
The aim of the present review was to summarize the evidence implicating the association between myopia and glaucoma, the possible underlying mechanisms for this relation, and the controversies surrounding detection of glaucomatous changes in coexisting myopia.
Numerous studies have shown that increasing categories of myopia are associated with a higher risk for optic neuropathy and glaucoma-like visual field defects. Recently, some high-resolution imaging modalities have been developed that aid further detection of the microanatomical changes of the optic nerve head and thus may provide a new insight to explain the association between myopia and glaucoma. Although the highly myopic eye usually shows many structural and functional defects that are difficult to distinguish from those caused by glaucoma, some new methods have been introduced to better differentiate between these changes.
The interaction of myopia with glaucoma risk remains complex, largely because of the retinal and nerve fiber layer damage that occurs in myopia alone. Whether to treat for glaucoma relies on the suspicion level of the clinician who must consider other risk factors for vision loss. Ultimately, it is the progression of glaucoma-like findings that determines whether a myopic patient has glaucoma.
本综述旨在总结近视与青光眼之间关联的证据、这种关系可能的潜在机制,以及围绕在并存近视情况下检测青光眼性改变的争议。
众多研究表明,近视程度增加与视神经病变及青光眼样视野缺损的较高风险相关。最近,已开发出一些高分辨率成像模式,有助于进一步检测视神经乳头的微观解剖变化,从而可能为解释近视与青光眼之间的关联提供新的见解。尽管高度近视眼通常表现出许多难以与青光眼所致结构和功能缺陷相区分的缺陷,但已引入一些新方法来更好地区分这些变化。
近视与青光眼风险之间的相互作用仍然复杂,主要是因为仅近视就会发生视网膜和神经纤维层损伤。是否治疗青光眼取决于临床医生的怀疑程度,临床医生必须考虑其他视力丧失风险因素。最终,是青光眼样表现的进展决定了近视患者是否患有青光眼。