未治疗精神病期的持续时间是否具有社会中介效应？
Are the effects of duration of untreated psychosis socially mediated?
机构信息
Professor, Departments of Psychiatry, Psychology, and Epidemiology & Biostatistics, The University of Western Ontario, London, Ontario.
出版信息
Can J Psychiatry. 2014 Oct;59(10):518-22. doi: 10.1177/070674371405901004.
Abstract
Investigation of possible mechanisms by which longer duration of untreated psychosis (DUP) could influence treatment outcomes has focused primarily on evidence for neurotoxic effects. It is also possible that longer DUP has psychosocial effects, which could mediate its impact on outcomes. The evidence of relevance to such socially toxic effects is reviewed, with particular reference to the possible role of social support. There is no definite evidence for social support as a mediator of the influence of DUP, but further investigation of this issue is warranted.
摘要
对可能导致未治疗精神病期（DUP）延长影响治疗结果的机制的研究主要集中在神经毒性效应的证据上。也有可能是 DUP 时间延长产生了心理社会效应，从而对结果产生影响。本文回顾了与这种社会毒性效应相关的证据，特别提到了社会支持可能发挥的作用。虽然没有明确的证据表明社会支持是 DUP 影响的中介，但有必要进一步研究这个问题。
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