Huang Fang, Zhao Ang, Chen Ren Jie, Kan Hai Dong, Kuang Xing Ya
Department of Occupational Medicine, Yangpu Hospital, Tongji University School of Medicine, Shanghai 200090, China; Department of Occupational Medicine, Yangpu District Central Hospital, Shanghai 200090, China; Institute of Occupational and Environmental Medicine, Medical School, Tongji University School of Medicine, Shanghai 200090, China.
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai 200032, China.
Biomed Environ Sci. 2015 Jan;28(1):76-9. doi: 10.3967/bes2015.008.
The association between ambient temperature and acute exacerbation of chronic bronchitis (AECB) was still unknown. Therefore, we performed an epidemiological study in a large hospital of Shanghai to explore the relationship about temperature and outpatient visit for AECB. We adopted a quasi-Poisson generalized additive models and distributed lag nonlinear models to estimate the accumulative effects of temperature on AECB across multiple days. We found significant non-linear effects of cold temperature on hospital visits for AECB, and the potential effect of cold temperature might last more than 2 weeks. The relative risks of extreme cold (first percentiles of temperature throughout the study period) and cold (10th percentile of temperature) temperature over lags 0-14 d were 2.98 [95% confidence intervals (CI): 1.77, 5.04] and 1.63 (95% CI: 1.21, 2.19), compared with the 25th percentile of temperature. However, we found no positive association between hospital visits and hot weather. This study showed that exposure to both extreme cold and cold temperatures were associated with increased outpatient visits for AECB in a large hospital of Shanghai.
环境温度与慢性支气管炎急性加重（AECB）之间的关联尚不清楚。因此，我们在上海的一家大型医院进行了一项流行病学研究，以探讨温度与AECB门诊就诊之间的关系。我们采用了准泊松广义相加模型和分布滞后非线性模型来估计温度在多日期间对AECB的累积影响。我们发现低温对AECB医院就诊有显著的非线性影响，低温的潜在影响可能持续超过2周。与温度的第25百分位数相比，在滞后0 - 14天期间，极端寒冷（整个研究期间温度的第1百分位数）和寒冷（温度的第10百分位数）温度的相对风险分别为2.98 [95%置信区间（CI）：1.77, 5.04]和1.63（95% CI：1.21, 2.19）。然而，我们未发现医院就诊与炎热天气之间存在正相关。这项研究表明，在上海的一家大型医院中，暴露于极端寒冷和寒冷温度均与AECB门诊就诊增加有关。
