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小儿腹部手术后经腹横肌平面阻滞用于术后镇痛的疗效

Efficacy of surgical transversus abdominis plane block for postoperative pain relief following abdominal surgery in pediatric patients.

作者信息

Lapmahapaisan Saowaphak, Tantemsapya Niramol, Aroonpruksakul Naiyana, Maisat Wiriya, Suraseranivongse Suwannee

机构信息

Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Paediatr Anaesth. 2015 Jun;25(6):614-20. doi: 10.1111/pan.12607. Epub 2015 Jan 9.

Abstract

BACKGROUND

Transversus abdominis plane (TAP) block is a promising effective method for postoperative pain control after major abdominal surgery. Using a landmark technique, it is easily performed, but its popularity has decreased because of less efficacy due to inaccurate injection and the potential for intraperitoneal organ damage. Ultrasound-guided TAP block provides better results and less complications, but it requires experienced operators. Surgically administered TAP (sTAP) block is a simple technique and may cause less complications. This study was aimed to determine the efficacy of sTAP on postoperative pain control in pediatric patients following a major abdominal surgery, compared with local anesthetic infiltration and no block.

METHODS

This stratified, randomized controlled trial was conducted in pediatric patients, below the age of 15 years, who underwent non-laparoscopic major abdominal surgery. Patients were allocated into three groups. The control group received no block; the LA group received 0.25% bupivacaine for local wound infiltration; and the sTAP group received 0.25% bupivacaine for TAP block performed by a surgeon before abdominal wall closure. Parameter records included the incidence of inadequate pain control, time to first analgesic, opioid requirement within 24 h, and complications of these techniques.

RESULTS

Fifty-four patients were recruited. There was no significant difference in the incidence of inadequate pain control (P = 0.589). The median time to first analgesic was 380 min in the sTAP group compared with 370 and 420 min in the LA and control groups, respectively (95%CI = 193-567, 121-619, and 0-1012; P = 0.632). The median dose of total opioid requirement (calculated as fentanyl-equivalent dose) was 1.95, 2.05, and 2.04 μg·kg(-1) ·24 h(-1) in the sTAP, LA, and control groups, respectively (IQR = 0.65, 2.20; 0.59, 3.32; 0.38, 2.60; P = 0.723). No complications of sTAP block were detected.

CONCLUSIONS

There was no significant advantage of the sTAP block over local infiltration or no intervention for postoperative pain control in pediatric patients undergoing non-laparoscopic major abdominal surgeries.

摘要

背景

腹横肌平面(TAP)阻滞是一种用于腹部大手术后控制术后疼痛的有效方法。采用体表定位技术操作简便,但由于注射不准确导致效果欠佳以及存在损伤腹腔内器官的风险,其应用已减少。超声引导下TAP阻滞效果更佳且并发症更少,但需要经验丰富的操作人员。外科手术实施的TAP(sTAP)阻滞是一种简单的技术,并发症可能较少。本研究旨在确定sTAP阻滞对接受腹部大手术的儿科患者术后疼痛控制的效果,并与局部麻醉药浸润和不进行阻滞进行比较。

方法

本分层随机对照试验在15岁以下接受非腹腔镜腹部大手术的儿科患者中进行。患者被分为三组。对照组不进行阻滞;局部麻醉药(LA)组接受0.25%布比卡因进行局部伤口浸润;sTAP组在关闭腹壁前由外科医生进行TAP阻滞并注射0.25%布比卡因。记录的参数包括疼痛控制不佳的发生率、首次使用镇痛药的时间、24小时内阿片类药物需求量以及这些技术的并发症。

结果

共招募了54例患者。疼痛控制不佳的发生率无显著差异(P = 0.589)。sTAP组首次使用镇痛药的中位时间为380分钟,而LA组和对照组分别为370分钟和420分钟(95%CI = 193 - 567,121 - 619,0 - 1012;P = 0.632)。sTAP组、LA组和对照组阿片类药物总需求量的中位剂量(以芬太尼等效剂量计算)分别为1.95、2.05和2.04 μg·kg⁻¹·24 h⁻¹(四分位间距 = 0.65,2.20;0.59,3.32;0.38,2.60;P = 0.723)。未检测到sTAP阻滞的并发症。

结论

对于接受非腹腔镜腹部大手术的儿科患者,sTAP阻滞在术后疼痛控制方面相对于局部浸润或不干预并无显著优势。

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