Chemical Biology Laboratory, Department of Chemistry, Aarhus University, DK-8000, Aarhus C, Denmark.
Nat Prod Rep. 2015 Apr;32(4):605-32. doi: 10.1039/c4np00106k.
In this review we investigate the use of complex ester fragment couplings within natural product total synthesis campaigns. We first outline the different biosynthetic and chemical strategies for performing complex ester couplings and on this mechanistic background we then present and discuss a collection of successful examples from the literature.
在本次综述中,我们研究了在天然产物全合成中使用复杂酯片段偶联的情况。我们首先概述了实现复杂酯偶联的不同生物合成和化学策略,在此基础上,我们展示并讨论了文献中的一系列成功实例。