Prevalence and risk factors of inadequate cervical dilation following laminaria insertion in second-trimester abortion--case control study.

作者信息

Ben-Ami Ido, Stern Sharon, Vaknin Zvi, Smorgick Noam, Schneider David, Halperin Reuvit

机构信息

Department of Obstetrics and Gynecology, Assaf Harofe Medical Center, Zerifin, Israel, affiliated with the Sackler School of Medicine, Tel-Aviv University.

出版信息

Contraception. 2015 Apr;91(4):308-12. doi: 10.1016/j.contraception.2014.12.012. Epub 2015 Jan 7.

OBJECTIVE

The objective was to explore the prevalence of and risk factors for inadequate cervical dilation following insertion of a single set of laminaria in women scheduled for dilation & evacuation (D&E) at 14-24 weeks' gestation.

STUDY DESIGN

We retrospectively reviewed all cases of women who underwent pregnancy termination by D&E at 14-24 weeks' gestation between January 2003 and December 2013. All cases in which the surgical procedure was cancelled due to failure to achieve adequate cervical dilation after a single set of laminaria inadequate cervical dilation were included. The control group was women who underwent D&E following adequate cervical dilation after a single set of laminaria, and were matched according to gestational week in a ratio of 1:3.

RESULTS

The overall dilation failure rate was 3.2%, with 4.0% among the induced-abortion patients and 1.5% among the patients with fetal demise (p=.002). Patients who had inadequate cervical dilation had lower rates of gravidity (p=.002) and previous spontaneous vaginal delivery (p<.001), along with higher rates of primigravidity, nulliparity (p<.001), previous cesarean section/s (p=.041), previous abdominal surgeries (p=.001) and previous cervical procedures (p=.003), compared to controls. A multivariable logistic regression analysis revealed two risk factors for inadequate cervical dilation following laminaria insertion, namely, previous cesarean section (p=.002) and previous cervical procedure (p<.001), whereas increased gravidity was found to protect against inadequate cervical dilation (p=.002).

CONCLUSIONS

Previous cesarean section/s, cervical procedures and primigravidity were found to be risk factors for failure to achieve adequate cervical dilation after a single set of laminaria. Women who are scheduled for D&E, and in whom one of these risk factors exists, might benefit from additional interventions to achieve better cervical preparation.