Kubisa Bartosz, Bocheńska Anna, Piotrowska Maria, Dec Paweł, Lesińska Anna, Kubisa Anna, Wójcik Janusz, Pieróg Jarosław, Grodzki Tomasz
Pneumonol Alergol Pol. 2015;83(1):45-9. doi: 10.5603/PiAP.2015.0006.
Primary pulmonary lymphoma accounts only 0,5% of all primary lung neoplasms. Mucosa-associated lymphoid tissue (MALT) lymphoma is a low grade B-cell extranodal lymphoma. It is a quite infrequent entity, however it constitutes from 72% to 90% of all pulmonary lung lymphomas. Long-term stimulation of bronchus-associated lymphoid tissue by antigens, smoking, inflammatory disorders or autoimmune diseases are thought to be leading to the development of MALT lymphoma. We present the case of primary pulmonary mucosa-associated lymphoid tissue lymphoma. A 76-year-old man with a history of heavy smoking (22.5 pack years) was admitted to the hospital for a further diagnostics of an abnormal finding in the right lung visualized on the chest X-ray. The diagnostic process, including imagining studies did not reveal the etiology of a lesion in the right lung. The patient was qualified for surgical diagnostics. The histological finding confirmed extranodal marginal low-grade B-cell lymphoma of mucosa -associated lymphoid tissue.
原发性肺淋巴瘤仅占所有原发性肺肿瘤的0.5%。黏膜相关淋巴组织(MALT)淋巴瘤是一种低级别B细胞结外淋巴瘤。它是一种相当罕见的疾病,然而它占所有肺淋巴瘤的72%至90%。抗原、吸烟、炎症性疾病或自身免疫性疾病对支气管相关淋巴组织的长期刺激被认为会导致MALT淋巴瘤的发生。我们报告一例原发性肺黏膜相关淋巴组织淋巴瘤病例。一名有重度吸烟史(22.5包年)的76岁男性因胸部X线显示右肺异常发现而入院进一步诊断。包括影像学检查在内的诊断过程未揭示右肺病变的病因。该患者符合手术诊断条件。组织学检查结果证实为黏膜相关淋巴组织的结外边缘低级别B细胞淋巴瘤。