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藏药白脉软膏(文中符号所示)治疗桡骨远端骨折后腕关节功能障碍的病例对照研究

[Case-control study on tibetan Baimai ointment (see symbol in text) for the treatment of wrist-dysfunction after distal radius fracture].

作者信息

Zhang Xing-ping, Xu Gen-rong, Xu Shan-qiang, Lu Ze-ming, Huang Lei

机构信息

Wangjin Hospital of China Academy of Medical Sciences, Beijing, China.

出版信息

Zhongguo Gu Shang. 2014 Nov;27(11):920-4.

PMID:25577914
Abstract

OBJECTIVE

To evaluate efficacy and safety of Baimai ointment (see symbol in text) in the treatment of wrist-dysfunction after distal radius fracture.

METHODS

From April, 2011 to June, 2012, 43 patients with distal radius fracture were treated with plaster fixation. All the patients were divided into two group: test group and control group. Twenty-one patients in test group and 22 in control group, and the baseline was balance (P > 0.05). The 21 patients in test group were treated with Baimai ointment (see symbol in text), fomentation, functional exercises. The 22 patients in control group were treated with placebo, fomentation, functional exercises. Foment affected side wrist with wet towel in 20 min before medication, with the temperature between 50 degrees C and 60 degrees C. Smear drugs uniformly in range of 3 cm in the vicinity of palm stripes after drying (about 3 g) and take functional exercises for the activities of wrist and hand. Continuous follow the program per 8 hours once and follow-up for 8 weeks. The Wrist's pain was assessed with VAS. The wrist's activities were measured with the protractor of orthopedic. Measure The grip strength was measured with dynamometer. The wrist's function were assessed with the table of Cooney.

RESULTS

The test group had a significantly better results than those of control group in the extent of wrist's pain throughout the treatment (P < 0.001), and grip strength on the 28th day and the 56th day (P < 0.05), and Cooney functional assessment on the 56th day (P < 0.05). Wrist's activities had no significane difference throughout the 8 weeks (P > 0.05). There were no drug adverse reactions occurred.

CONCLUSION

Tibetan Baimai ointment (see symbol in text) has the treatment of wrist-dysfunction after distal radius fracture for external use, which can reduce the extent of wrist's pain, promote grip strength recovery in the middle and late of process, promote wrist's function recovery latterly, and safety for external use.

摘要

目的

评价白脉软膏(文中符号)治疗桡骨远端骨折后腕关节功能障碍的有效性和安全性。

方法

2011年4月至2012年6月,43例桡骨远端骨折患者采用石膏固定治疗。所有患者分为两组:试验组和对照组。试验组21例,对照组22例,基线均衡(P>0.05)。试验组21例患者采用白脉软膏(文中符号)、热敷、功能锻炼治疗。对照组22例患者采用安慰剂、热敷、功能锻炼治疗。用药前用湿毛巾热敷患侧手腕20分钟,温度在50℃至60℃之间。擦干后在掌纹附近3厘米范围内均匀涂抹药物(约3克),并对手腕和手部进行功能锻炼。每8小时连续按程序进行一次,随访8周。采用视觉模拟评分法(VAS)评估腕部疼痛。用骨科量角器测量腕关节活动度。用握力计测量握力。用Cooney量表评估腕关节功能。

结果

试验组在整个治疗过程中腕部疼痛程度(P<0.001)、第28天和第56天的握力(P<0.05)以及第56天的Cooney功能评估(P<0.05)均明显优于对照组。8周内腕关节活动度无显著差异(P>0.05)。未发生药物不良反应。

结论

藏药白脉软膏(文中符号)外用治疗桡骨远端骨折后腕关节功能障碍,可减轻腕部疼痛程度,促进病程中晚期握力恢复,促进后期腕关节功能恢复,且外用安全。

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