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血液透析期间透析内并发症谱及其管理:单中心经验

Spectrum of intradialytic complications during hemodialysis and its management: a single-center experience.

作者信息

Singh Rana Gopal, Singh Shivendra, Rathore Surendra Singh, Choudhary Tauhidul Alam

出版信息

Saudi J Kidney Dis Transpl. 2015 Jan;26(1):168-72. doi: 10.4103/1319-2442.148771.

Abstract

Hemodialysis (HD) is one of the important modalities of renal replacement therapy in acute renal failure (ARF) as well as chronic renal failure (CRF). This study was performed to evaluate the various intradialytic complications that occur during HD and their management. This is a retrospective study performed in patients who underwent conventional HD during the period of 1 January 2000 to 31 December 2011 at our center. Clinical details, various complications faced and their management were retrieved from dialysis case sheets. A total of 2325 patients of renal failure (790 ARF and 1535 CRF patients) were assessed for the intradialytic complications of HD. During the study period, there were 12,785 bicarbonate dialyses performed on these patients. In the ARF patients, the common intradialytic complications were: Hypotension, seen in 1296 sessions (30.4%), nausea and vomiting seen in 1125 sessions (26.4%), fever and chills seen in 818 sessions (19.2%), headache seen in 665 sessions (15.6%), cramps seen in 85 sessions (2.0%), chest pain and back pain seen in 82 sessions (1.92%), hypoglycemia seen in 77 sessions (1.8%), first-use syndrome seen in 72 sessions (1.7%) and femoral hematoma seen in 31 sessions (0.73%). In the CRF group, common complications were hypotension in 2230 sessions (26.1%), nausea and vomiting in 1211 sessions (14.2%), fever and chills in 1228 sessions (14.4%), chest pain and back pain in 1108 cases (13.0%), hypertension in 886 sessions (10.4%), headache in 886 sessions (10.4%), cramps in 256 sessions (3.0%), hematoma in 55 sessions (0.64%), intracerebral hemorrhage in three sessions (0.03%) and catheter tip migration in three sessions (0.03%). There is a need for special attention for the diagnosis and management of intradialytic complications of HD because such complications could be managed successfully without the need for termination of the dialysis procedure.

摘要

血液透析(HD)是急性肾衰竭(ARF)及慢性肾衰竭(CRF)肾脏替代治疗的重要方式之一。本研究旨在评估HD过程中发生的各种透析期间并发症及其处理方法。这是一项回顾性研究,研究对象为2000年1月1日至2011年12月31日期间在本中心接受常规HD治疗的患者。从透析病历中获取临床细节、所面临的各种并发症及其处理方法。共评估了2325例肾衰竭患者(790例ARF患者和1535例CRF患者)的HD透析期间并发症。在研究期间,对这些患者进行了12785次碳酸氢盐透析。在ARF患者中,常见的透析期间并发症有:低血压,见于1296次透析(30.4%);恶心和呕吐,见于1125次透析(26.4%);发热和寒战,见于818次透析(19.2%);头痛,见于665次透析(15.6%);痉挛,见于85次透析(2.0%);胸痛和背痛,见于82次透析(1.92%);低血糖,见于77次透析(1.8%);首次使用综合征,见于72次透析(1.7%);股部血肿,见于31次透析(0.73%)。在CRF组中,常见并发症有:低血压,见于2230次透析(26.1%);恶心和呕吐,见于1211次透析(14.2%);发热和寒战,见于1228次透析(14.4%);胸痛和背痛,见于1108例透析(13.0%);高血压,见于886次透析(10.4%);头痛,见于886次透析(10.4%);痉挛,见于256次透析(3.0%);血肿,见于55次透析(0.64%);脑出血,见于3次透析(0.03%);导管尖端移位,见于3次透析(0.03%)。需要特别关注HD透析期间并发症的诊断和处理,因为此类并发症无需终止透析程序即可成功处理。

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