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肝移植23年后出现症状的新发嗜铬细胞瘤:一例报告并文献复习

A symptomatic de novo pheochromocytoma 23 years after liver transplantation: a case report and review of the literature.

作者信息

Montenovo M I, Jalikis F G, Hoch B, Bakthavatsalam R

机构信息

Division of Transplantation, Department of Surgery, University of Washington, Seattle, WA, USA.

Department of Anatomic Pathology, University of Washington, Seattle, WA, USA.

出版信息

Case Rep Transplant. 2014;2014:934385. doi: 10.1155/2014/934385. Epub 2014 Dec 14.

Abstract

We report a case of subacute onset of headaches and tremors with a newly discovered adrenal pheochromocytoma 23 years after an orthotopic liver transplantation and provide a review of the scarce literature regarding endocrine malignancies in liver transplant recipients. We describe the clinical presentation, diagnostic work-up, and management. This is the second case report in the literature of a de novo pheochromocytoma after solid organ transplantation. It shows that new-onset common symptoms in transplant recipients are always challenging and deserve a very thorough work-up until the cause of the symptoms is elucidated. A broad differential diagnosis should always be included in the study of any abnormalities in this patient population.

摘要

我们报告了一例在原位肝移植23年后新发肾上腺嗜铬细胞瘤并伴有亚急性头痛和震颤的病例,并对肝移植受者内分泌恶性肿瘤的稀缺文献进行了综述。我们描述了临床表现、诊断检查和治疗方法。这是文献中第二例实体器官移植后新发嗜铬细胞瘤的病例报告。它表明,移植受者出现的新发常见症状总是具有挑战性,在症状原因得以阐明之前,值得进行非常全面的检查。在研究该患者群体的任何异常情况时,始终应包括广泛的鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbf2/4279711/1d2958323ec1/CRIT2014-934385.001.jpg

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