Tabel Yilmaz, Aksoy Özlem, Elmas Ahmet Taner, Çelik Serkan Fazli
Department of Pediatric Nephrology, Faculty of Medicine, University of İnonu , Malatya , Turkey.
Blood Press. 2015 Apr;24(2):119-23. doi: 10.3109/08037051.2014.992194. Epub 2015 Jan 12.
In this study, we aimed to investigate the blood pressure (BP) profile in children with a unilateral functioning solitary kidney (UFSK). A group of 49 patients between the ages of 5 and 18 years, and 30 healthy controls between the ages of 6 and 16 years were investigated. Gender, weight, height and body mass index (BMI) of patients and controls were recorded. BP profile was determined by ambulatory BP monitoring (ABPM). We have observed a higher risk of hypertension compared with healthy children. Also, masked hypertension is more frequently in the patients group and white-coat hypertension was observed in the control group. The mean night-time systolic BP (SBP) load (p = 0.01) and 24-h diastolic BP (DBP) load (p = 0.008) of children with multicystic dysplastic kidney (MCDK) was significantly higher than the healthy group. The mean night-time SBP load (p = 0.001) of children with unilateral renal agenesis (URA) and 24-h DBP load (p = 0.003) of children with unilateral atrophic or hypoplastic kidney were significantly higher than healthy group. We showed that the children with a solitary kidney had increased risk of hypertension. ABPM reflects the BP profile more precisely than casual BP measurement and it can be used to evaluate white-coat and masked hypertension in children with a solitary kidney.
在本研究中，我们旨在调查单侧功能性孤立肾（UFSK）患儿的血压（BP）情况。对一组年龄在5至18岁的49例患者以及30例年龄在6至16岁的健康对照者进行了调查。记录了患者和对照者的性别、体重、身高和体重指数（BMI）。通过动态血压监测（ABPM）确定血压情况。我们观察到与健康儿童相比，高血压风险更高。此外，患者组隐匿性高血压更为常见，而对照组则观察到白大衣高血压。多囊性发育不良肾（MCDK）患儿的夜间平均收缩压（SBP）负荷（p = 0.01）和24小时舒张压（DBP）负荷（p = 0.008）显著高于健康组。单侧肾缺如（URA）患儿的夜间平均SBP负荷（p = 0.001）以及单侧萎缩或发育不全肾患儿的24小时DBP负荷（p = 0.003）显著高于健康组。我们表明，孤立肾患儿患高血压的风险增加。与偶然测量血压相比，ABPM能更准确地反映血压情况，并且可用于评估孤立肾患儿的白大衣高血压和隐匿性高血压。
