Ritter Philip L, Ory Marcia G, Laurent Diana D, Lorig Kate
Stanford Patient Education Research Center, School of Medicine, Stanford University, 1000 Welch Road Rd., Suite 204, Palo Alto, CA 94304 USA.
Health Science Center, Texas A&M University, College Station, TX USA.
Transl Behav Med. 2014 Dec;4(4):398-406. doi: 10.1007/s13142-014-0277-9.
Depression often accompanies chronic illness. Study aims included determining (1) the level of current depression (Patient Health Questionnaire (PHQ)-8 ≥ 10) for two sets of Chronic Disease Self-Management Programs (CDSMP) participants; (2) if depression or other outcomes improved for those with PHQ-8 ≥ 10; and (3) if outcomes differed for participants with or without depression. This study utilized longitudinal secondary data analysis of depression cohorts (PHQ-8 ≥ 10) from two independent translational implementations of the CDSMP, small-group (N = 175) and Internet-based (N = 110). At baseline, 27 and 55 % of the two samples had PHQ-8 10 or greater. This decreased to 16 and 37 % by 12 months (p < 0.001). Both depressed and non-depressed cohorts demonstrated improvements in most 12-month outcomes (pain, fatigue, activity limitations, and medication adherence). The CDSMP was associated with long-term improvements in depression regardless of delivery mode or location, and the programs appeared beneficial for participants with and without depression.
抑郁症常伴随慢性病出现。研究目的包括确定：（1）两组慢性病自我管理项目（CDSMP）参与者当前的抑郁水平（患者健康问卷（PHQ）-8≥10）；（2）PHQ-8≥10的患者的抑郁或其他结果是否有所改善；以及（3）有抑郁和无抑郁的参与者的结果是否存在差异。本研究对来自CDSMP的两个独立转化实施项目（小组形式，N = 175；基于互联网形式，N = 110）的抑郁队列（PHQ-8≥10）进行纵向二次数据分析。在基线时，两个样本中分别有27%和55%的人PHQ-8为10或更高。到12个月时，这一比例降至16%和37%（p < 0.001）。抑郁和非抑郁队列在大多数12个月的结果（疼痛、疲劳、活动受限和药物依从性）方面均有改善。无论提供方式或地点如何，CDSMP都与抑郁的长期改善相关，并且这些项目对有抑郁和无抑郁的参与者似乎都有益。
