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作为答复。

In reply.

作者信息

Xu Binghe, Seidman Andrew, Chan Stephen

机构信息

Department of Medical Oncology, Cancer Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

出版信息

Oncologist. 2015 Jan;20(1):88. doi: 10.1634/theoncologist.2014-0284.

DOI:10.1634/theoncologist.2014-0284
PMID:25589501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4294611/
Abstract

Many factors contribute to patient survival in metastatic breast cancer and other late-stage cancers. It is doubtful that adjuvant therapy causes a worse survival outcome. This being said, should resistance develop following adjuvant therapy, the patient needs to be offered a first-line solution that is free of cross-resistance.

摘要

许多因素影响转移性乳腺癌和其他晚期癌症患者的生存。辅助治疗导致更差生存结果的说法值得怀疑。话虽如此,如果辅助治疗后出现耐药,需要为患者提供一线无交叉耐药的治疗方案。

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本文引用的文献

1
Adjuvant therapy-related shortening of survival (ATRESS): an underrated phenomenon.辅助治疗相关的生存缩短(ATRESS):一种被低估的现象。
Oncologist. 2015 Jan;20(1):88. doi: 10.1634/theoncologist.2014-0273.
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A pooled analysis of gemcitabine plus docetaxel versus capecitabine plus docetaxel in metastatic breast cancer.吉西他滨联合多西他赛与卡培他滨联合多西他赛治疗转移性乳腺癌的汇总分析
Oncologist. 2014 May;19(5):443-52. doi: 10.1634/theoncologist.2013-0428. Epub 2014 Apr 4.
3
The 2011 EBCTCG polychemotherapy overview.2011年早期乳腺癌协作组多药化疗综述。
Lancet. 2012 Feb 4;379(9814):390-2. doi: 10.1016/S0140-6736(11)61823-0. Epub 2011 Dec 5.
4
30 years' follow up of randomised studies of adjuvant CMF in operable breast cancer: cohort study.可手术乳腺癌辅助性CMF随机研究的30年随访:队列研究
BMJ. 2005 Jan 29;330(7485):217. doi: 10.1136/bmj.38314.622095.8F. Epub 2005 Jan 13.
5
Effect of adjuvant chemotherapy on outcome in patients with metastatic breast carcinoma treated with first-line doxorubicin-containing chemotherapy.辅助化疗对接受含阿霉素一线化疗的转移性乳腺癌患者预后的影响。
Cancer. 2001 Mar 15;91(6):1079-89. doi: 10.1002/1097-0142(20010315)91:6<1079::aid-cncr1103>3.0.co;2-s.
6
Combination chemotherapy as an adjuvant treatment in operable breast cancer.联合化疗作为可手术乳腺癌的辅助治疗方法。
N Engl J Med. 1976 Feb 19;294(8):405-10. doi: 10.1056/NEJM197602192940801.