Zhang Junli, Xu Jing, Du Xiaoxing, Yu Yunsong, Lv Fangfang
1 Department of Infectious Disease, 2 Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
J Thorac Dis. 2014 Dec;6(12):E281-8. doi: 10.3978/j.issn.2072-1439.2014.12.17.
Rhodococcus equi (R. equi) is an uncommon gram positive organism. It is a rare but recognized pathogen in humans and has emerged as an important cause of morbidity and mortality among immunocompromised patients. Generally, R. equi infection needs combined treatment with effective antibiotics, and often requires the immune adjuvant therapy. Here we reported a 49-year-old man presented dyspnea with fever, skin ulcer for 5 months, and the final diagnosis was diffuse large B cell lymphoma with R. equi septicemia and pneumonia, the treatment was failure, the blood culture was always positive during the course of disease, though he was given combined treatment with effective antibiotics, perhaps the immune reconstitution or immune supportive treatment was more important.
马红球菌是一种不常见的革兰氏阳性菌。它是人类中一种罕见但已被认识的病原体，并且已成为免疫功能低下患者发病和死亡的重要原因。一般来说，马红球菌感染需要联合使用有效的抗生素进行治疗，并且常常需要免疫辅助治疗。在此我们报告一名49岁男性，出现发热伴呼吸困难、皮肤溃疡5个月，最终诊断为弥漫性大B细胞淋巴瘤合并马红球菌败血症和肺炎，治疗失败，在病程中血培养一直呈阳性，尽管给予了有效的联合抗生素治疗，但也许免疫重建或免疫支持治疗更为重要。
