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尽管之前进行了100分钟的心肺复苏,但疑似肺栓塞患者经抢救性溶栓后神经功能恢复良好。

Good neurological recovery after rescue thrombolysis of presumed pulmonary embolism despite prior 100 minutes CPR.

作者信息

Wu Jiang-Ping, Gu Dan-Yan, Wang Sheng, Zhang Zhen-Jun, Zhou Jian-Cang, Zhang Rui-Feng

机构信息

1 Department of Emergency Medicine, The Second People's Hospital of Yiwu City, Yiwu 322002, China ; 2 Department of Critical Care Medicine, 3 Department of Respiratory Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.

出版信息

J Thorac Dis. 2014 Dec;6(12):E289-93. doi: 10.3978/j.issn.2072-1439.2014.12.23.

DOI:10.3978/j.issn.2072-1439.2014.12.23
PMID:25590010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4283306/
Abstract

We reported the case of a 70-year-old man who was admitted to neurologic wards for recurrent syncope for 3 years. Unfortunately, just 2 hours after his admission, he suddenly collapsed and failed to return of spontaneous circulation (ROSC) after a 100-minute standard cardiopulmonary resuscitation (CPR). Fortunately, he was timely suspected to have pulmonary embolism (PE) based on his sedentary lifestyle, elevated D-dimer and markedly enlarged right ventricle chamber on bedside echocardiography. After a rescue thrombolytic alteplase therapy, he was successfully resuscitated and good neurological recovery was achieved.

摘要

我们报告了一名70岁男性的病例,他因反复晕厥3年入住神经科病房。不幸的是,入院仅2小时后,他突然晕倒,在进行100分钟的标准心肺复苏(CPR)后未能恢复自主循环(ROSC)。幸运的是,基于他久坐的生活方式、D-二聚体升高以及床边超声心动图显示右心室明显增大,他被及时怀疑患有肺栓塞(PE)。经过溶栓药物阿替普酶的抢救治疗,他成功复苏,神经功能恢复良好。

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本文引用的文献

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Thrombolytic treatment (alteplase; rt-Pa) in acute massive pulmonary embolism and cardiopulmonary arrest.急性大面积肺栓塞和心肺骤停的溶栓治疗(阿替普酶;重组组织型纤溶酶原激活剂)
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JAMA. 2014 Jun 18;311(23):2414-21. doi: 10.1001/jama.2014.5990.
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Evidence-based diagnosis and thrombolytic treatment of cardiac arrest or periarrest due to suspected pulmonary embolism.疑似肺栓塞导致的心搏骤停或心搏骤停前期的循证诊断和溶栓治疗。
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