Department of Physics and Measurements, University of Chemistry and Technology, Prague, Czech Republic.
Department of Biochemistry and Microbiology, University of Chemistry and Technology, Prague, Czech Republic.
Biotechnol Adv. 2015 Nov 1;33(6 Pt 2):1108-19. doi: 10.1016/j.biotechadv.2015.01.002. Epub 2015 Jan 13.
By definition, the nonthermal plasma (NTP) is partially ionized gas where the energy is stored mostly in the free electrons and the overall temperature remains low. NTP is widely used for many years in various applications such as low-temperature plasma chemistry, removal of gaseous pollutants, in gas-discharge lamps or surface modification. However, during the last ten years, NTP usage expanded to new biological areas of application like plasma microorganisms' inactivation, ready-to-eat food preparation, biofilm degradation or in healthcare, where it seems to be important for the treatment of cancer cells and in the initiation of apoptosis, prion inactivation, prevention of nosocomial infections or in the therapy of infected wounds. These areas are presented and documented in this paper as a review of representative publications.
根据定义，非热等离子体（NTP）是部分电离气体，其中能量主要存储在自由电子中，整体温度保持较低。NTP 多年来广泛应用于各种领域，如低温等离子体化学、气态污染物的去除、在气体放电灯或表面改性中。然而，在过去的十年中，NTP 的使用扩展到了新的生物应用领域，如等离子体微生物失活、即食食品制备、生物膜降解或在医疗保健中，在这些领域，NTP 似乎对癌细胞的治疗和细胞凋亡的启动很重要，朊病毒失活、预防医院获得性感染或感染性伤口的治疗。这些领域在本文中作为代表性出版物的综述进行了介绍和记录。
