Zenone T
Unité de médecine interne, département de médecine, centre hospitalier de Valence, 179, boulevard Maréchal-Juin, 26953 Valence cedex 9, France.
Rev Med Interne. 2015 Jul;36(7):457-66. doi: 10.1016/j.revmed.2014.11.010. Epub 2015 Jan 13.
Recurrent fever of unknown origin is probably the most difficult to diagnose subtype of fever of unknown origin. It represents between 18 and 42% of the cases in large series of patients with fever of unknown origin. The limited literature data do not allow one to construct a diagnostic algorithm. However, the diagnostic strategy is different from classic fever of unknown origin. The spectrum of causative disorders is different from continuous fever with less infections and tumors. Among systemic inflammatory diseases, adult-onset Still's disease is the most common cause. More than 50% of the cases remain unexplained. Hereditary recurrent fevers, the prototype of autoinflammatory diseases, are now more easily discuss in a young adult.
不明原因复发性发热可能是不明原因发热中最难诊断的亚型。在大量不明原因发热患者系列中，它占病例的18%至42%。有限的文献数据无法构建诊断算法。然而，其诊断策略不同于经典的不明原因发热。致病疾病谱与持续发热不同，感染和肿瘤较少。在系统性炎症性疾病中，成人斯蒂尔病是最常见的病因。超过50%的病例病因不明。遗传性复发性发热作为自身炎症性疾病的原型，现在在年轻成年人中更容易被讨论。
