健康足月新生儿出生后即刻呼气中的二氧化碳。
Exhaled carbon dioxide in healthy term infants immediately after birth.
机构信息
Center for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, Canada; Neonatal Services, The Royal Women's Hospital, Melbourne, Australia; The Ritchie Center, Monash University, Melbourne, Australia; Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada; Critical Care Stream, Murdoch Children Research Institute, Melbourne, Australia.
The Ritchie Center, Monash University, Melbourne, Australia.
出版信息
J Pediatr. 2015 Apr;166(4):844-9.e1-3. doi: 10.1016/j.jpeds.2014.12.007. Epub 2015 Jan 13.
OBJECTIVE
To measure exhaled carbon dioxide (ECO2) in term infants immediately after birth.
STUDY DESIGN
Infants >37 weeks gestation born at The Royal Women's Hospital, Melbourne, Australia were eligible. A combined flow sensor and mainstream carbon dioxide (CO2) analyzer was placed in series proximal to a facemask to measure ECO2 and tidal volumes in the first 120 seconds after birth.
RESULTS
Term infants (n = 20) with a mean (SD) birth weight of 2976 (697) g and gestational age of 38 (2) weeks were included. Infants took a median (range) 3 (1-8) breaths before ECO2 was detected. The median (range) of maximum ECO2 was 51 (40-73) mm Hg at 70 (21-106) seconds after birth. Within the first 10 breaths, CO2 increased from 0-27 (22-34) mm Hg. The median (IQR) tidal volume during the breaths without CO2 was 1.2 (0.8-3.1) mL/kg compared with 7.3 (3.2-10.9) mL/kg during the first 10 breaths where CO2 was exhaled.
CONCLUSIONS
The first breaths for an infant after birth did not contain ECO2. With aeration of the distal gas exchange regions, tidal volume and ECO2 significantly increased. ECO2 can be used to monitor lung aeration immediately after birth.
目的
测量出生后即刻的足月婴儿呼气二氧化碳（ECO2）。
研究设计
符合条件的婴儿为在澳大利亚墨尔本皇家妇女医院出生、胎龄>37 周的足月婴儿。在出生后最初 120 秒内，将组合流量传感器和主流二氧化碳（CO2）分析仪串联放置在面罩近端，以测量 ECO2 和潮气容积。
结果
纳入 20 例胎龄 38（2）周、出生体重 2976（697）g 的足月婴儿。婴儿在检测到 ECO2 前平均（SD）呼吸 3（1-8）次。出生后 70（21-106）秒时，最大 ECO2 的中位数（范围）为 51（40-73）mm Hg。在最初的 10 次呼吸中，CO2 从 0-27（22-34）mm Hg 增加。无 CO2 呼出时的潮气容积中位数（IQR）为 1.2（0.8-3.1）mL/kg，而在呼出 CO2 的前 10 次呼吸中为 7.3（3.2-10.9）mL/kg。
结论
出生后婴儿的第一口气不含 ECO2。随着远端气体交换区的通气，潮气量和 ECO2 显著增加。ECO2 可用于在出生后立即监测肺通气。
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