Mascarelli Patricia E, Elmore Stacey A, Jenkins Emily J, Alisauskas Ray T, Walsh Mary, Breitschwerdt Edward B, Maggi Ricardo G
Intracellular Pathogens Research Laboratory (IPRL), Center for Comparative Medicine and Translational Research College of Veterinary Medicine, North Carolina State University, NC, USA.
Department of Veterinary Microbiology, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N EB4, Canada.
Res Vet Sci. 2015 Apr;99:58-9. doi: 10.1016/j.rvsc.2014.12.011. Epub 2014 Dec 16.
Because of the relatively low biodiversity within arctic ecosystems, arctic foxes, Vulpes lagopus, could serve as sentinels for the study of changes in the ecology of vector-borne zoonotic pathogens. The objective of this study was to determine the molecular prevalence of 5 different genera of vector borne pathogens (Anaplasma, Babesia, Bartonella, Ehrlichia, and Hemotropic Mycoplasma spp.) using blood collected from 28 live-trapped arctic foxes from the region of Karrak Lake, Nunavut, Canada. Bartonella henselae (n = 3), Mycoplasma haemocanis (n = 1), Ehrlichia canis (n = 1), and an Anaplasma sp. (n = 1) DNA were PCR amplified and subsequently identified by sequencing. This study provides preliminary evidence that vector borne pathogens, not typically associated with the arctic ecosystem, exist at low levels in this arctic fox population, and that vector exposure, pathogen transmission dynamics, and changes in the geographic distribution of pathogens over time should be investigated in future studies.
由于北极生态系统内生物多样性相对较低，北极狐（Vulpes lagopus）可作为研究媒介传播的人畜共患病原体生态变化的哨兵。本研究的目的是利用从加拿大努纳武特地区卡拉湖地区28只活体诱捕的北极狐采集的血液，确定5种不同属的媒介传播病原体（无形体属、巴贝斯虫属、巴尔通体属、埃立克体属和嗜血性支原体属）的分子流行率。通过PCR扩增了汉赛巴尔通体（n = 3）、犬血支原体（n = 1）、犬埃立克体（n = 1）和一种无形体属（n = 1）的DNA，并随后通过测序进行了鉴定。本研究提供了初步证据，表明在这个北极狐种群中存在通常与北极生态系统无关的媒介传播病原体，且数量较低，未来的研究应调查媒介暴露、病原体传播动态以及病原体地理分布随时间的变化情况。
