Department of Anaesthesia and Intensive Care, Haukeland University Hospital, Bergen, Norway; Department of Clinical Medicine, University of Bergen, Norway.
Department of Neurology, Haukeland University Hospital, Bergen, Norway; Department of Biological and Medical Psychology, University of Bergen, Norway.
Resuscitation. 2015 Apr;89:13-8. doi: 10.1016/j.resuscitation.2014.12.021. Epub 2015 Jan 14.
Neuropsychological testing has uncovered cognitive impairment in cardiac arrest survivors with good neurologic outcome according to the cerebral performance categories. We investigated cognitive function and health-related quality of life four years after cardiac arrest.
Thirty cardiac arrest survivors over the age of 18 in cerebral performance category 1 or 2 on hospital discharge completed the EQ-5D-5L and HADS questionnaires prior to cognitive testing using the Cambridge Neuropsychological Test Automated Battery. The results were compared with population norms.
Twenty-nine per cent of patients were cognitively impaired. The pattern of cognitive impairment reflects dysfunction in the medial temporal lobe, with impaired short-time memory and executive function slightly but distinctly affected. There was a significant reduction in quality of life on the EQ-VAS, but not on the EQ index.
Cognitive impairment four years after cardiac arrest affected more than one quarter of the patients. Short-term memory was predominantly affected.
神经心理学测试显示，根据脑功能预后分类，心脏骤停后神经系统恢复良好的幸存者存在认知障碍。我们在心脏骤停后 4 年调查了认知功能和健康相关的生活质量。
30 名年龄在 18 岁以上、出院时脑功能预后分类为 1 或 2 的心脏骤停幸存者，在使用剑桥神经心理学测试自动电池进行认知测试之前，完成了 EQ-5D-5L 和 HADS 问卷。结果与人群正常值进行了比较。
29%的患者存在认知障碍。认知障碍的模式反映了内侧颞叶的功能障碍，短时记忆和执行功能受损，但程度较轻。在 EQ-VAS 上，生活质量显著下降，但 EQ 指数没有。
心脏骤停后 4 年，超过四分之一的患者存在认知障碍。记忆受损主要影响短期记忆。
