Pani P K, Kishore S, Naithani S
Indian Veterinary Research Institute, Uttar Pradesh.
Avian Dis. 1989 Oct-Dec;33(4):615-21.
Bryan standard strain of Rous sarcoma virus (BS-RSV) of subgroup A was inoculated into heavy and light breeds of chicken embryos via chorioallantoic membrane (CAM) to ascertain cell-mediated immune response, as measured by a leukocyte migration inhibition (LMI) test. Chicks hatched from eggs with pock-positive CAMs were more likely to develop liver tumors than those hatched from eggs with pock-negative CAMs. Chicks that developed tumors usually had a positive cell-mediated immune response, and those that were negative for liver tumor were negative, based on the LMI test.
将A亚群的劳氏肉瘤病毒（BS-RSV）的布莱恩标准毒株通过绒毛尿囊膜（CAM）接种到重型和轻型品种的鸡胚中，以通过白细胞迁移抑制（LMI）试验来确定细胞介导的免疫反应。从CAM出现痘斑阳性的鸡蛋孵化出的雏鸡比从CAM出现痘斑阴性的鸡蛋孵化出的雏鸡更易发生肝肿瘤。根据LMI试验，发生肿瘤的雏鸡通常具有阳性的细胞介导免疫反应，而肝肿瘤阴性的雏鸡则为阴性。
