Nkala Busisiwe, Khunwane Mamakiri, Dietrich Janan, Otwombe Kennedy, Sekoane Itumeleng, Sonqishe Bulelwa, Gray Glenda
a Perinatal HIV Research Unit , University of the Witwatersrand , Johannesburg , South Africa.
AIDS Care. 2015;27(6):697-702. doi: 10.1080/09540121.2014.993352. Epub 2015 Jan 19.
This paper reports on Kganya Motsha Adolescent Centre, an adolescent program specifically established to provide voluntary counseling and testing as well as management of HIV-positive young people in Soweto, South Africa. A retrospective cross-sectional analysis, using clinic records of young people accessing services from 2008 to 2012, was conducted. Of the 11,522 who tested, 7689 (67%) were females. The total number of HIV infections was 410, with an HIV prevalence of 3.6% (95% CI 3.2-3.9%). More females (332, 4% vs. 72, 2%; p < 0.0001) were HIV-infected than males. Of those testing HIV positive, 109 (26.5%) had a median CD4 cell count of 491 (IQR 345-686) cells/mm(3). Only 12/410 individuals (2.9%) were eligible for antiretroviral treatment and 10 (2.4%) of those successfully received treatment. The program observed that young people testing HIV positive would not return for follow up blood specimens or confirmatory results. Future programs should consider innovative ways of retaining adolescents in care to reduce potential HIV transmissions that could lead to deteriorating health.
本文报道了南非索韦托的Kganya Motsha青少年中心，这是一个专门设立的青少年项目，旨在提供自愿咨询与检测以及对艾滋病毒呈阳性的年轻人进行管理。利用2008年至2012年期间接受服务的年轻人的临床记录进行了回顾性横断面分析。在接受检测的11522人中，7689人（67%）为女性。艾滋病毒感染总数为410人，艾滋病毒流行率为3.6%（95%置信区间3.2 - 3.9%）。感染艾滋病毒的女性（332人，4%）比男性（72人，2%）更多（p < 0.0001）。在艾滋病毒检测呈阳性的人中，109人（26.5%）的CD4细胞计数中位数为491（四分位间距345 - 686）个细胞/mm³。只有12/410人（2.9%）符合抗逆转录病毒治疗条件，其中10人（2.4%）成功接受了治疗。该项目发现，艾滋病毒检测呈阳性的年轻人不会回来进行后续血液样本检测或确认检测结果。未来的项目应考虑采用创新方法让青少年持续接受护理，以减少可能导致健康状况恶化的潜在艾滋病毒传播。
