• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于扩张施莱姆管的新型装置:一项形态学研究:在对施莱姆管进行粘弹扩张后植入施特格曼管扩张器,可使管腔永久性扩张,并使小梁网扩张,且无并发症。

Novel device for expanding Schlemm's canal: a morphological study: Implantation of the Stegmann Canal Expander following viscodilation of Schlemm's canal resulted in permanent expansion of the canal lumen and distension of the trabecular meshwork without complications.

作者信息

Grieshaber Matthias C, Stegmann Robert, Grieshaber Hans R, Meyer Peter

机构信息

Department of Ophthalmology, University of Basel, Basel, Switzerland Department of Ophthalmology, Medical University of Southern Africa, Medunsa, South Africa.

Department of Ophthalmology, Medical University of Southern Africa, Medunsa, South Africa.

出版信息

Br J Ophthalmol. 2015 Jul;99(7):875-7. doi: 10.1136/bjophthalmol-2014-305540. Epub 2015 Jan 18.

DOI:10.1136/bjophthalmol-2014-305540
PMID:25601045
Abstract

This study was performed to assess any changes in Schlemm's canal (SC) in human autopsy eyes possibly resulting from the injection of a viscoelastic substance and implantation of a new device (the Stegmann Canal Expander, SCE) into SC. After the surgical procedure, eyes were fixed, dissected into quartered segments and examined using light and scanning electron microscopy. Tissue sections displayed a marked dilation of SC and of the collector channels compared with untreated control sections. The SC walls were disrupted in some areas due to viscodilation, but not due to SCE implantation. In all eyes, the entire 9-mm length of the SCE was positioned inside the canal, keeping the canal wide open. The SCE diameter of 240 μm remained unchanged after implantation. Injection of a viscoelastic substance into SC leads to marked dilation of SC and collector channels. Implanting the SCE into SC allowed persistent expansion of SC and stretching of the trabecular meshwork. This may increase the permeability of the trabecular meshwork, reduce its resistance to aqueous humour and maintain circumferential flow within SC. Experimental and clinical studies should determine the impact of this new canal expander in terms of lowering intraocular pressure in glaucoma surgery.

摘要

本研究旨在评估在人类尸检眼中,向施莱姆管(SC)注射粘弹性物质以及在SC中植入新装置(施特格曼管扩张器,SCE)可能导致的SC变化。手术操作后,将眼睛固定,切成四等份并使用光学显微镜和扫描电子显微镜进行检查。与未处理的对照切片相比,组织切片显示SC和集合管明显扩张。SC壁在某些区域因粘弹性扩张而破坏,但并非因植入SCE所致。在所有眼中,SCE的整个9毫米长度均位于管内,使管保持开放。植入后SCE的直径240μm保持不变。向SC注射粘弹性物质会导致SC和集合管明显扩张。将SCE植入SC可使SC持续扩张并拉伸小梁网。这可能会增加小梁网的通透性,降低其对房水的阻力并维持SC内的周向流动。实验和临床研究应确定这种新型管扩张器在青光眼手术中降低眼压方面的影响。

相似文献

1
Novel device for expanding Schlemm's canal: a morphological study: Implantation of the Stegmann Canal Expander following viscodilation of Schlemm's canal resulted in permanent expansion of the canal lumen and distension of the trabecular meshwork without complications.用于扩张施莱姆管的新型装置:一项形态学研究:在对施莱姆管进行粘弹扩张后植入施特格曼管扩张器,可使管腔永久性扩张,并使小梁网扩张,且无并发症。
Br J Ophthalmol. 2015 Jul;99(7):875-7. doi: 10.1136/bjophthalmol-2014-305540. Epub 2015 Jan 18.
2
Stegmann Canal Expander for canaloplasty: A novel technique.用于巩膜沟成形术的施特格曼巩膜沟扩张器:一种新技术。
Eur J Ophthalmol. 2018 Jul;28(4):472-478. doi: 10.1177/1120672117753699. Epub 2018 Mar 19.
3
Effects of a Schlemm canal scaffold on collector channel ostia in human anterior segments.施莱姆管支架对人眼前节集合管开口的影响。
Exp Eye Res. 2014 Feb;119:70-6. doi: 10.1016/j.exer.2013.12.011. Epub 2013 Dec 24.
4
Segmental variability of the trabecular meshwork in normal and glaucomatous eyes.正常眼和青光眼眼中小梁网的节段性变异性。
Invest Ophthalmol Vis Sci. 1994 Oct;35(11):3841-51.
5
Comparisons of Schlemm's canal and trabecular meshwork morphologies between juvenile and primary open angle glaucoma.青少年型和原发性开角型青光眼的房水流出道和小梁网形态比较。
Exp Eye Res. 2021 Sep;210:108711. doi: 10.1016/j.exer.2021.108711. Epub 2021 Aug 2.
6
Retroperfusion studies of the aqueous outflow system. Part 2: Studies in human eyes.房水流出系统的逆行灌注研究。第2部分:人体眼睛的研究。
Invest Ophthalmol Vis Sci. 1995 Nov;36(12):2466-75.
7
Morphological factors associated with giant vacuoles with I-pores in Schlemm's canal endothelial cells of human eyes: A serial block-face scanning electron microscopy study.人眼房水流出通道 Schlemm 管内皮细胞中具有 I 型孔的巨大空泡的形态学相关因素:一个连续块面扫描电子显微镜研究。
Exp Eye Res. 2021 Apr;205:108488. doi: 10.1016/j.exer.2021.108488. Epub 2021 Feb 9.
8
Canaloplasty: circumferential viscodilation and tensioning of Schlemm's canal using a flexible microcatheter for the treatment of open-angle glaucoma in adults: interim clinical study analysis.小梁切开术:使用可弯曲微导管对施莱姆管进行环形粘弹扩张和张紧,用于治疗成人开角型青光眼:中期临床研究分析
J Cataract Refract Surg. 2007 Jul;33(7):1217-26. doi: 10.1016/j.jcrs.2007.03.051.
9
Schlemm's canal and trabecular meshwork morphology in high myopia.高度近视眼中的施莱姆管和小梁网形态
Ophthalmic Physiol Opt. 2018 May;38(3):266-272. doi: 10.1111/opo.12451.
10
Effects of viscoelastic injection into Schlemm's canal in primate and human eyes: potential relevance to viscocanalostomy.向灵长类动物和人眼的施莱姆管内注射粘弹性物质的效果:与粘小管切开术的潜在相关性。
Ophthalmology. 2002 Apr;109(4):786-92. doi: 10.1016/s0161-6420(01)01006-5.

引用本文的文献

1
Flap-sparing canaloplasty: a modified approach to Schlemm's canal.保留瓣膜的小梁切开术:一种改良的施累姆管手术方法。
Graefes Arch Clin Exp Ophthalmol. 2019 Aug;257(8):1729-1732. doi: 10.1007/s00417-019-04329-8. Epub 2019 May 6.
2
Medical Management of Glaucoma in the 21st Century from a Canadian Perspective.从加拿大视角看21世纪青光眼的医学管理
J Ophthalmol. 2016;2016:6509809. doi: 10.1155/2016/6509809. Epub 2016 Nov 8.
3
[Channelography and mechanism of action in canaloplasty].[小梁成形术的房角造影及作用机制]
Ophthalmologe. 2015 Apr;112(4):319-24. doi: 10.1007/s00347-014-3163-4.