Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Ophthalmology. 2015 May;122(5):903-8. doi: 10.1016/j.ophtha.2014.12.003. Epub 2015 Jan 17.
To investigate the factors affecting visual acuity after cataract surgery in patients with retinitis pigmentosa (RP).
Retrospective, observational study.
We retrospectively reviewed the charts of a consecutive series of 40 patients with RP who underwent cataract surgery.
The changes in preoperative and postoperative best-corrected visual acuity (BCVA) were measured. We investigated the relation between preoperative mean deviation (MD) value on the Humphrey Field Analyzer (HFA: the central 10-2 program; Humphrey Instruments, Inc, San Leandro, CA) and final BCVA. We also investigated the relationship between preoperative ellipsoid zone (EZ; also called the inner/outer segment junction) conditions and final BCVA. In addition, we showed the prevalence of macular complications and capsule complications.
The BCVA, slit-lamp biomicroscopic analysis, visual field, and optical coherence tomography (OCT) were obtained.
The mean of the BCVA significantly improved after cataract surgery from 0.76 (range, -0.08 to 2.30) to 0.45 (range, -0.18 to 2.00) (P < 0.005). However, final BCVA did not improve in 30 eyes (53.6%). The preoperative MD value and the final BCVA were significantly correlated, and the final BCVA significantly improved in the less advanced RP group (MD was ≥-15 decibels [dB]). The final BCVA was significantly better in the group in which preoperative OCT showed a normal EZ than in the groups in which the EZ was abnormal or not visible. Posterior capsular opacification was observed in 47 eyes (83.9%), and 23 eyes (41.1%) underwent YAG laser capsulotomy within a mean follow-up time of 3 years.
Final BCVA in approximately half of the eyes improved after cataract surgery in patients with RP. The preoperative ophthalmic examinations that may reflect macular (or foveal) function, such as HFA 10-2 program and OCT, are important parameters to assess postoperative visual outcome.
探讨色素性视网膜炎（RP）患者白内障术后视力的影响因素。
回顾性、观察性研究。
我们回顾性分析了连续 40 例接受白内障手术的 RP 患者的病历。
测量术前和术后最佳矫正视力（BCVA）的变化。我们研究了 Humphrey 视野分析仪（HFA：中央 10-2 程序；Humphrey 仪器公司，加利福尼亚州圣莱安德罗）术前平均偏差（MD）值与最终 BCVA 之间的关系。我们还研究了术前椭圆体带（EZ；也称为内/外节交界处）状况与最终 BCVA 的关系。此外，我们还展示了黄斑并发症和囊袋并发症的患病率。
获得 BCVA、裂隙灯生物显微镜分析、视野和光学相干断层扫描（OCT）。
白内障手术后 BCVA 平均值从 0.76（范围：-0.08 至 2.30）显著提高至 0.45（范围：-0.18 至 2.00）（P <0.005）。然而，30 只眼（53.6%）的最终 BCVA 没有改善。术前 MD 值与最终 BCVA 显著相关，在进展较慢的 RP 组中，最终 BCVA 显著提高（MD 为≥-15 分贝[dB]）。术前 OCT 显示正常 EZ 的组的最终 BCVA 明显优于 EZ 异常或不可见的组。在 47 只眼（83.9%）中观察到后囊混浊，23 只眼（41.1%）在平均 3 年的随访时间内行 YAG 激光囊切开术。
RP 患者白内障手术后约一半的眼最终 BCVA 提高。HFA 10-2 程序和 OCT 等可能反映黄斑（或中心凹）功能的术前眼科检查是评估术后视力结果的重要参数。
