Andreasen Frances M, Kahler Bill
Specialist Consultant in Dental Trauma, Copenhagen, Denmark; Visiting Lecturer in Dental Traumatology in the Department of Primary Dental Care, Dental Institute, King's College, London, United Kingdom.
School of Dentistry, University of Queensland, Brisbane, Australia.
J Endod. 2015 Mar;41(3):299-308. doi: 10.1016/j.joen.2014.11.015. Epub 2015 Jan 15.
Pulpal reactions after acute dental injury have been puzzling for many clinicians. The management of dental trauma and an understanding of clinical and treatment factors in outcomes arose from multivariate statistical analyses of archive material from Copenhagen.
The aim of this article was to review the works of this period with respect to pulpal reaction after acute mechanical trauma. These traumas include luxation, avulsion, root fracture, and crown fracture. A PubMed search identified other literature where multivariate analysis was used, and these results were compared with earlier pioneering studies.
This article will describe pulpal responses after the said acute injuries and outline the competition that takes place between ingrowth of a new neurovascular system into the traumatized tissue versus bacterial invasion. If there is an intact neurovascular supply to the pulp, then the same immunologic defenses that are found in the rest of the body can function and defend against infection. If this is disturbed in any way, alterations in the pulp (eg, pulp canal obliteration, resorption processes) or pulp death (pulp necrosis) will occur. Intermediary stations in pulpal response (ie, transient apical breakdown) mimicked the cardinal signs of pulp necrosis, which could be reversible and lead to pulpal healing. These processes will also be addressed with respect to a more conservative treatment approach. In young patients, it is of the utmost importance that pulp vitality be maintained to ensure continued root growth and development and an intact dentition.
急性牙外伤后的牙髓反应一直困扰着许多临床医生。对牙外伤的处理以及对临床和治疗因素与治疗结果关系的理解源于对哥本哈根存档材料的多变量统计分析。
本文的目的是回顾这一时期关于急性机械性外伤后牙髓反应的研究。这些外伤包括牙齿松动、脱位、根折和冠折。通过PubMed检索确定了其他使用多变量分析的文献,并将这些结果与早期的开创性研究进行了比较。
本文将描述上述急性损伤后的牙髓反应,并概述新的神经血管系统向创伤组织内生长与细菌入侵之间的竞争。如果牙髓有完整的神经血管供应,那么身体其他部位存在的相同免疫防御机制就能发挥作用并抵御感染。如果这种供应以任何方式受到干扰,牙髓就会发生改变(如牙髓腔闭锁、吸收过程)或牙髓死亡(牙髓坏死)。牙髓反应的中间阶段(即短暂性根尖病变)类似于牙髓坏死的主要症状,可能是可逆的,并导致牙髓愈合。这些过程也将结合更保守的治疗方法进行讨论。在年轻患者中,维持牙髓活力对于确保牙根持续生长发育和牙列完整至关重要。