Gianella P, Gasche-Soccal P, van Delden C, Hachulla A L, Rochat T
Départment de chirurgie, HUG, Genève.
Rev Med Suisse. 2014 Nov 19;10(451):2202-7.
Aspergillus pulmonary infection causes a spectrum of diverse diseases according to host immunity. The two major entities are invasive pulmonary aspergillosis and chronic pulmonary aspergillosis. The later can be divided into aspergilloma, then into chronic cavitary, more or less fibrosing aspergillosis, and finally into chronic necrotizing aspergillosis, or semiinvasive aspergillosis. The present article reviews this complex classification, which is necessary to reflect the diverse clinical aspect of the disease. Allergic broncho-pulmonary aspergillosis (ABPA), which is more a hypersensitivity reaction than an infectious process, will not be discussed here.
根据宿主免疫力,曲霉肺部感染会引发一系列不同的疾病。两个主要类型是侵袭性肺曲霉病和慢性肺曲霉病。后者可分为曲菌球,进而分为慢性空洞性、或多或少纤维化的曲霉病,最后分为慢性坏死性曲霉病或半侵袭性曲霉病。本文回顾了这一复杂的分类,这对于反映该疾病多样的临床情况是必要的。变应性支气管肺曲霉病(ABPA)更多的是一种超敏反应而非感染过程,本文将不对此进行讨论。