Graham Kathryn G, Nasir Asad
Arnot Ogden Medical Center Residency Program, Arnot Health, Elmira, NY, USA.
Departmemnt of Pulmonology, Arnot Health, Elmira, NY, USA.
Am J Case Rep. 2019 Aug 18;20:1220-1224. doi: 10.12659/AJCR.915893.
BACKGROUND Aspergillus spores have the ability to affect patients with or without intact immune systems; because of this disease's wide patient involvement it deserves a place on the differential diagnosis list, with endocarditis and tuberculosis, for those presenting with new pulmonary nodules or cavitation. CASE REPORT This case report involves the presentation, diagnosis, and treatment of a 69-year-old female who presented with new rapidly progressing cavitary lung lesions in the setting of copious administration of systemic steroid use. Given the patient's past history of alcoholism and environmental exposure, her case was not straight forward in regard to a diagnosis. Ultimately, she was diagnosed with chronic cavity pulmonary aspergillosis in the setting of chronic immunosuppression secondary to systemic steroid administration. Due to her convoluted medical history and the poor differential diagnosis list, there was a delay in final diagnosis. CONCLUSIONS This case report and clinical review aims to prevent anchoring when the patient's presentation is not straight forward and aims to remind the clinician of the importance of a differential diagnosis.
背景 曲霉菌孢子能够感染免疫系统健全或受损的患者;鉴于这种疾病涉及的患者范围广泛,对于出现新的肺结节或空洞的患者,它在鉴别诊断清单中应占有一席之地,与心内膜炎和结核病一同考虑。病例报告 本病例报告涉及一名69岁女性的临床表现、诊断和治疗,该患者在大量使用全身性类固醇的情况下出现了新的快速进展的空洞性肺部病变。鉴于患者有酗酒史和环境暴露史,其病例在诊断方面并不简单。最终,她被诊断为在全身性类固醇给药继发的慢性免疫抑制情况下的慢性空洞型肺曲霉病。由于她复杂的病史和鉴别诊断清单不完善,最终诊断出现了延迟。结论 本病例报告和临床综述旨在防止在患者表现不明确时形成思维定式,并旨在提醒临床医生鉴别诊断的重要性。