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[重度腰椎发育不良性脊柱滑脱的治疗]

[The treatment of severe lumbar dysplastic spondylolisthesis].

作者信息

Guo Zhaoqing, Chen Zhongqiang, Qi Qiang, Li Weishi, Zeng Yan, Sun Chuiguo

机构信息

Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China. Email:

Department of Orthopedics, Peking University Third Hospital, Beijing 100191, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2014 Nov;52(11):845-50.

Abstract

OBJECTIVE

To summarize the clinical characteristics of severe lumbar dysplastic spondylolisthesis, and to investigate the effectiveness of the posterior surgery including decompression, partial reduction with instrumentations and interbody fusion.

METHODS

Twelve patients of severe lumbar dysplastic spondylolisthesis treated between March 2007 and February 2012 were studied retrospectively. Twelve patients include 10 female and 2 male patients with an average age of 10.7 years (9-17 years). All of their spondylolisthetic level was L5 vertebrae. None of them were effective after regular conservative treatment. Eleven of 12 patients were treated surgically through a posterior decompression and instrumented reduction. One case was treated by L5 vertebrectomy and reduction of L4 onto sacrum. Their levels of instrumentations were L4-S1 in 8 patients and L5-S1 in 4 patients. All of 12 patients were fused via interbody fusion. The visual analog scale(VAS), Oswestry disability index (ODI), Japanese Orthopaedic Association(JOA) score, slip angle, percentage slip, lumbar lordosis, sagittal balance were used as outcome measures.

RESULTS

All of these patients were followed up regularly with an average follow-up of 32 months (6-64 months). Five of these 12 patients suffered postoperative nerve root impairment, including impairment of unilateral and bilateral L5 nerve roots. At the latest follow-up, only 1 case was still suffering from the weakness of unilateral peroneal long and short muscles, the other 4 patients recovered totally. The degree of their spondylolisthesis was reduced II degrees or more, and their slip angles decreased from 35.6 degree preoperatively to 9.8 degree postoperatively. The VAS, ODI , JOA, lumbar lordosis and sagittal balance were improved postoperatively. No instrumentation loosening or rupture was found.

CONCLUSIONS

In patients with severe lumbar dysplastic spondylolisthesis, isolated posterior decompression, reduction with internal fixation may lead to a satisfactory clinical outcomes. Surgical reduction is helpful to improve the interbody contact area, thus possibly improve the fusion rate. At the same time, reduction may reduce or correct the lumbar-sacral kyphosis, recover the normal lumbar lordosis and normal sagittal alignment with an excellent cosmetic result. The incidence of the postoperative nerve impairment is high because of the stretching of L5 nerve roots secondary to the reduction, but most of the patients with postoperative nerve impairment may recover gradually.

摘要

目的

总结重度腰椎发育不良性椎体滑脱的临床特点,探讨后路减压、器械辅助部分复位及椎间融合手术的疗效。

方法

回顾性研究2007年3月至2012年2月间收治的12例重度腰椎发育不良性椎体滑脱患者。12例患者中,女性10例,男性2例,平均年龄10.7岁(9 - 17岁)。所有患者椎体滑脱均发生于L5椎体。经正规保守治疗均无效。12例患者中11例行后路减压及器械辅助复位手术。1例患者行L5椎体切除及L4骶骨化手术。器械固定节段,8例为L4 - S1,4例为L5 - S1。12例患者均行椎间融合术。采用视觉模拟评分法(VAS)、Oswestry功能障碍指数(ODI)、日本矫形外科学会(JOA)评分、滑脱角、滑脱百分比、腰椎前凸及矢状面平衡作为疗效评价指标。

结果

所有患者均获定期随访,平均随访32个月(6 - 64个月)。12例患者中有5例术后出现神经根损伤,包括单侧及双侧L5神经根损伤。末次随访时,仅1例患者仍存在单侧腓骨长短肌肌力减弱,其余4例患者完全恢复。患者椎体滑脱程度均降低Ⅱ度及以上,滑脱角从术前的35.6°降至术后的9.8°。术后VAS、ODI、JOA、腰椎前凸及矢状面平衡均得到改善。未发现内固定松动或断裂。

结论

对于重度腰椎发育不良性椎体滑脱患者,单纯后路减压、内固定复位可取得满意的临床疗效。手术复位有助于增加椎间接触面积,从而可能提高融合率。同时,复位可减少或纠正腰骶后凸,恢复正常腰椎前凸及矢状面排列,外形美观。由于复位导致L5神经根牵拉,术后神经损伤发生率较高,但多数术后神经损伤患者可逐渐恢复。

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