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以全身性瘙痒为表现的格雷夫斯病

Generalised pruritus as a presentation of Grave's disease.

作者信息

Tan Ce, Loh Ky

出版信息

Malays Fam Physician. 2013 Apr 30;8(1):20-3. eCollection 2013.

Abstract

Pruritus is a lesser known symptom of hyperthyroidism, particularly in autoimmune thyroid disorders. This is a case report of a 27-year-old woman who presented with generalised pruritus at a primary care clinic. Incidental findings of tachycardia and a goiter led to the investigations of her thyroid status. The thyroid function test revealed elevated serum free T4 and suppressed thyroid stimulating hormone levels. The anti-thyroid antibodies were positive. She was diagnosed with Graves' disease and treated with carbimazole until her symptoms subsided. Graves' disease should be considered as an underlying cause for patients presenting with pruritus. A thorough history and complete physical examination are crucial in making an accurate diagnosis. Underlying causes must be determined before treating the symptoms.

摘要

瘙痒是甲状腺功能亢进症鲜为人知的症状,在自身免疫性甲状腺疾病中尤为如此。本文报告了一名27岁女性患者,她在基层医疗诊所出现全身瘙痒症状。偶然发现的心动过速和甲状腺肿促使对其甲状腺状况进行检查。甲状腺功能检查显示血清游离T4升高,促甲状腺激素水平降低。抗甲状腺抗体呈阳性。她被诊断为格雷夫斯病,并接受了甲巯咪唑治疗,直至症状缓解。对于出现瘙痒症状的患者,应考虑格雷夫斯病为潜在病因。详尽的病史和全面的体格检查对于准确诊断至关重要。在治疗症状之前必须确定潜在病因。

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本文引用的文献

1
Hyperthyroidism in pregnancy.妊娠合并甲状腺功能亢进症。
Curr Opin Endocrinol Diabetes Obes. 2012 Oct;19(5):394-401. doi: 10.1097/MED.0b013e328357f3d5.
2
Urticaria and thyroid autoimmunity.荨麻疹与甲状腺自身免疫。
Thyroid. 2011 Apr;21(4):401-10. doi: 10.1089/thy.2010.0103.
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THYROTOXICOSIS: ITS SURGICAL ASPECTS.甲状腺毒症:外科学方面
Br Med J. 1935 Nov 30;2(3908):1034-7. doi: 10.1136/bmj.2.3908.1034.
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Graves' disease.格雷夫斯病
N Engl J Med. 2000 Oct 26;343(17):1236-48. doi: 10.1056/NEJM200010263431707.

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