Key Douglas J
J Drugs Dermatol. 2014 Dec;13(12):1485-9.
Radiofrequency has remained a staple procedure for the treatment of skin laxity as therapeutic heat thresholds effectively promote collagen remodeling. Nevertheless, comprehensive skin tightening involves both dermal and hypodermal collagen remodeling. However, transcutaneous radiofrequency is unable to deliver consistent and measurable temperatures to the hypodermal layers. Herein, we evaluated a newly emerging approach that provides precise and controlled subdermal heating is thermistor-controlled subdermal skin tightening (ThermiTight) using a percutaneous radiofrequency treatment probe.
A retrospective analysis of 35 patients was completed on patients having undergone ThermiTight for submental skin tightening. Treated sites included under-chin and under-chin and jowls. The ThermiTight probe temperature was set between 50 to 60 °C and was maintained using the thermistor integrated electrode. The probe was guided at a deliberate pace, treating a surface area of 3.0 cm2 every two minutes. The clinical endpoint was an epidermal temperature of 42 °C. Two blinded reviewers assessed photographs taken at baseline and 30 days post-procedure. They were randomly presented with a photograph and asked to rate the photograph using a 4.0 skin laxity scale.
The combined mean change comparing baseline and post-procedure skin laxity scores was -0.78, which was statistically significant (Table 2; P<0.0001). Each blinded reviewer correctly categorized photographs as either being "baseline" or "post-procedure" 89% of the time. No adverse events were reported.
These data demonstrate the safety and efficacy of the ThermiTIght procedure for the treatment of skin laxity.
射频一直是治疗皮肤松弛的主要方法,因为治疗热阈值能有效促进胶原蛋白重塑。然而,全面的皮肤紧致涉及真皮和皮下胶原蛋白重塑。然而,经皮射频无法将一致且可测量的温度传递到皮下层。在此,我们评估了一种新出现的方法,即使用经皮射频治疗探头进行热敏电阻控制的皮下皮肤紧致(ThermiTight),该方法可提供精确且可控的皮下加热。
对35例接受ThermiTight治疗颏下皮肤松弛的患者进行回顾性分析。治疗部位包括下巴下方以及下巴下方和下颌。ThermiTight探头温度设定在50至60°C之间,并使用集成热敏电阻的电极进行维持。探头以刻意的速度引导,每两分钟治疗3.0平方厘米的表面积。临床终点是表皮温度达到42°C。两名盲法评审员评估了基线和术后30天拍摄的照片。他们被随机展示一张照片,并被要求使用4.0皮肤松弛量表对照片进行评分。
比较基线和术后皮肤松弛评分的综合平均变化为-0.78,具有统计学意义(表2;P<0.0001)。每位盲法评审员在89%的时间内正确将照片分类为“基线”或“术后”。未报告不良事件。
这些数据证明了ThermiTIght程序治疗皮肤松弛的安全性和有效性。