Erlenwein J, Emons M, Hecke A, Nestler N, Wirz S, Bauer M, Meißner W, Petzke F
Klinik für Anästhesiologie, Zentrum Anästhesiologie, Rettungs- und Intensivmedizin, Universitätsmedizin Göttingen, Robert Koch Str. 40, 37075, Göttingen, Deutschland,
Anaesthesist. 2015 Mar;64(3):218-26. doi: 10.1007/s00101-014-2413-9.
Standardized treatment approaches can improve the quality of the management of acute postoperative pain.
The purpose of this study was to describe the content and structure of currently implemented standards for the management of acute postoperative pain in German hospitals and to better define the concept of a treatment standard for acute pain.
Written standardized treatment protocols from 68 hospitals for the management of acute postoperative pain were analyzed. The evaluation was based on the layout of processes, the baseline and rescue or on-demand analgesic medication and safety mechanisms.
A treatment standard per hospital separated for adults (68 standards) and children (27 standards) was identified and analyzed. A baseline medication was provided in all standards for adults and in 89% for children. Of the 95 standards 68% routinely combined opioids and non-opioids as a basis (78% for adults and 42% for children). A way to adapt the baseline medication was described more often in standards for adults. Of the standards for adults 91% (85% for children) contained provisions for rescue or on-demand analgesia and half of them (both adults and children) included an immediate-release opioid formulation, which was readily available. For adults the availability was regulated by a predefined process in 29% of the standards (8% for children). In cases of persisting pain, repetition of the rescue medication was generally possible in 63% of adult standards (54% for children) but within 1 h after the first dose in only 43% (30% for children). Intervention limitations for application of the rescue medication (e.g., a defined score on the numeric rating scale) were set in 63% of adult standards (54% for children). A follow-up assessment of the pain intensity after a rescue medication was only required in approximately half of the standards and safety information or mechanisms were only rarely included.
Content, structure and type of the evaluated treatment standards showed a considerable heterogeneity with respect to the availability of rescue and baseline medication. Safety aspects were not addressed in many cases. These findings show that despite the requirements of the German guidelines for treatment of perioperative and posttraumatic pain for treatment standards, there are still no practical recommendations with respect to contents and structure of such standards.
标准化治疗方法可提高急性术后疼痛管理的质量。
本研究旨在描述德国医院目前实施的急性术后疼痛管理标准的内容和结构,并更好地界定急性疼痛治疗标准的概念。
分析了68家医院用于急性术后疼痛管理的书面标准化治疗方案。评估基于流程布局、基础用药和解救或按需镇痛药物以及安全机制。
确定并分析了每家医院针对成人(68项标准)和儿童(27项标准)的治疗标准。所有成人标准和89%的儿童标准都提供了基础用药。在95项标准中,68%常规将阿片类药物和非阿片类药物联合作为基础用药(成人中为78%,儿童中为42%)。成人标准中更常描述调整基础用药的方法。成人标准中有91%(儿童为85%)包含解救或按需镇痛的规定,其中一半(成人和儿童)包括速释阿片类制剂,且随时可用。对于成人,29%的标准中通过预定义流程规定了其可用性(儿童为8%)。在持续疼痛的情况下,63%的成人标准(儿童为54%)通常允许重复使用解救药物,但仅43%(儿童为30%)在首次用药后1小时内允许。63%的成人标准(儿童为54%)设定了解救药物应用的干预限制(例如,数字评分量表上的特定分数)。大约只有一半的标准要求在使用解救药物后对疼痛强度进行随访评估,且很少包含安全信息或机制。
所评估的治疗标准在解救用药和基础用药的可用性方面,其内容、结构和类型存在相当大的异质性。很多情况下未涉及安全方面。这些发现表明,尽管德国围手术期和创伤后疼痛治疗指南对治疗标准有要求,但在这些标准的内容和结构方面仍没有实用的建议。