Zhang Jianjie, Li Zhiming, Wang Jinlin, Li Hui, Si Tujie, Deng Lihua, Qiu Shaohong
Department of occupational disease, Shenzhen hosptal for the prevention and treatment of occupational dieases, Shenzhen 518001, China.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2014 Dec;32(12):930-1.
To analyze the cause of misdiagnosis of occupational chronic n-hexane poisoning and to investigate the diagnosis and differential diagnosis of this disease.
The clinical data of 16 patients with occupational chronic n-hexane poisoning who had been misdiagnosed with other diseases were collected. The hospital they first visited, cause of misdiagnosis, clinical features, and the misdiagnosis rate among inpatients during the same period were retrospectively analyzed.
Sixteen of 62 patients hospitalized during the same period were misdiagnosed at the first visit; 11 cases were in the upper first-class hospitals, and 5 cases in the upper second-class hospitals; 5 cases were misdiagnosed as Green Barry syndrome, 2 cases as motor neuron disease, 2 cases as drug-induced peripheral neuropathy, 3 cases as periodic paralysis, and 4 cases had uncertain diagnosis.
Most doctors who work in ordinary hospitals do not know occupational chronic n-hexane poisoning, which is often misdiagnosed as general neuropathies or difficult diseases. The key to correct diagnosis is to know the patient's occupational history and clinical features.
分析职业性慢性正己烷中毒误诊原因，探讨该病的诊断及鉴别诊断方法。
收集16例曾被误诊为其他疾病的职业性慢性正己烷中毒患者的临床资料，对其首诊医院、误诊原因、临床特点以及同期住院患者中的误诊率进行回顾性分析。
同期住院的62例患者中，16例首诊误诊；其中11例误诊于上级甲等医院，5例误诊于上级乙等医院；5例误诊为格林-巴利综合征，2例误诊为运动神经元病，2例误诊为药物性周围神经病，3例误诊为周期性瘫痪，4例诊断不明确。
多数普通医院医生对职业性慢性正己烷中毒认识不足，常误诊为一般神经病或疑难病。正确诊断的关键在于了解患者职业史及临床特点。
