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[可植入式微波装置治疗肝癌的外科临床研究]

[Clinical study of the surgical treatment of hepatocarcinoma with an implantable microwave device].

作者信息

Gao B Y

出版信息

Zhonghua Wai Ke Za Zhi. 1989 Sep;27(9):531-4, 573-4.

PMID:2560964
Abstract

This article reports the surgical treatment to 51 patients with mid and advanced hepatocarcinoma by the self-made implantable microwave radiation apparatus from April, 1987 to April 1989. By way of histology, histochemistry, and electronic microscopy, we studied the killing effect on cancer cells, the range of the effect and the remarkable hemostatic mechanism of this implantable microwave device. Clinically, we developed six different methods of operate with the microwave. Without the need of blocking hepatic portal, this new approach simplifies the operation. The risk of iatrogenic cancerous diffusion and hemorrhage is also greatly reduced or prevented in hemihepatectomy. Initial results shows that the resection rate of the hepatocarcinoma went up from 20-42.5 percent to 74.5 percent. Microwave operation on 38 patients with advanced hepatocarcinoma reveals a survival rate of 75 percent over 6 months. The authors believe that this new operative method is effective in the treatment to advanced hepatic carcinoma, and prolongs the life of the patients.

摘要

本文报道了1987年4月至1989年4月期间,使用自制的可植入式微波辐射装置对51例中晚期肝癌患者进行的手术治疗。通过组织学、组织化学和电子显微镜检查,我们研究了这种可植入式微波装置对癌细胞的杀伤作用、作用范围以及显著的止血机制。临床上,我们开发了六种不同的微波手术方法。这种新方法无需阻断肝门,简化了手术操作。在半肝切除术中,医源性癌扩散和出血的风险也大大降低或得到预防。初步结果显示,肝癌的切除率从20% - 42.5%提高到了74.5%。对38例晚期肝癌患者进行的微波手术显示,6个月以上的生存率为75%。作者认为,这种新的手术方法对晚期肝癌的治疗有效,并延长了患者的生命。

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[Clinical study of the surgical treatment of hepatocarcinoma with an implantable microwave device].[可植入式微波装置治疗肝癌的外科临床研究]
Zhonghua Wai Ke Za Zhi. 1989 Sep;27(9):531-4, 573-4.
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[Microwave radiation treatment of liver cancer: animal experiment and preliminary clinical application].[肝癌的微波辐射治疗:动物实验与初步临床应用]
Zhonghua Wai Ke Za Zhi. 1989 Sep;27(9):538-40, 574.